Results 251 to 260 of about 1,451,454 (310)

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Multi-Omics Reveals Mechanisms of Metabolic Rejuvenation in Aged Mice and Pre-Frail Older Men by Losartan. [PDF]

Aging Cell
Bene MR, Zhang C, Westbrook R, Gabrawy M, Marx R, Wu Y, Khadeer M, Ubaida-Mohien C, Ferrucci L, Moaddel R, Le A, Walston JD, Lee JL, Abadir PM.   +13 more
europepmc   +1 more source

Cancer Treatment-Related Cardiotoxicity among Survivors of Childhood Cancer: A Comparative and Integrated View of Multiple Measures of Biological Age Acceleration. [PDF]

Cancer Epidemiol Biomarkers Prev
Meng X, Eulalio T, Oh K, Plonski NM, Shelton K, Mulder HL, Easton J, Zhang J, Walker EV, Neale G, Srivastava DK, Howell RM, Mandelblatt JS, Ky B, Dixon SB, Armstrong GT, Hudson MM, Ness KK, Wang Z.   +18 more
europepmc   +1 more source

Microbial-enzyme synergistic treatment stabilizes surface microbial communities and enhances flavor quality during tobacco leaf aging. [PDF]

Bioresour Bioprocess
Xu C, Sun Y, Fan Y, Lili Q, Zhang X, Ding M, Rong M.   +6 more
europepmc   +1 more source

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Older age treatment expectations

Journal of Clinical Psychology, 1986
The relationship between age and treatment expectation (TE) has been virtually ignored. This study assessed the TE and posthospital adjustment of 5,347 psychiatric patients, 4,361 younger (less than 55) and 986 older (greater than 55). Patients were evaluated on admission with self- and other rating adjustment scales and again at 3-months postdischarge.
L, Hyer, J, Collins
openaire   +2 more sources

Treatment of Early Vascular Ageing

Current Pharmaceutical Design, 2019
Artery disease can be identified from ankle-brachial index (peripheral artery disease), pulse wave velocity (arterial stiffness), carotid intima media thickness (atherosclerosis) and flow-mediated dilation (endothelial dysfunction). Arterial stiffness is a marker of cardiovascular disease associated with cardiovascular events. Increased vascular ageing
C, Antza, I, Doundoulakis, M, Natsis, V, Kotsis   +3 more
openaire   +2 more sources

Aging and Antithrombotic Treatment

Antioxidants & Redox Signaling
Significance: Several aging-related pathophysiological mechanisms have been described to contribute to increased thrombotic risk in the elderly, including oxidative stress, endothelial dysfunction, and platelet and coagulation cascade activation. Antithrombotic treatment in the elderly should be individualized.
Emanuele Valeriani, Simona Bartimoccia, Pasquale Pignatelli, Daniele Pastori   +3 more
openaire   +3 more sources