Results 61 to 70 of about 1,437,301 (294)

Diquat exacerbates oxidative stress and neuroinflammation by blocking the autophagic flux of microglia in the hippocampus

open access: yesEcotoxicology and Environmental Safety
Diquat (DQ) is a widely utilized nonselective herbicide that is primarily used to control a wide range of weeds and crop residues. It also has significant environmental implications. DQ exposure can cause severe damage to the central nervous system (CNS),
Ping Wang   +7 more
doaj   +1 more source

Hopping in the Glass Configuration Space: Subaging and Generalized Scaling Laws [PDF]

open access: yes, 2001
Aging dynamics in glassy systems is investigated by considering the hopping motion in a rugged energy landscape whose deep minima are characterized by an exponential density of states.
Bouchaud, Jean-Philippe   +2 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Effect of heat treatment on microstructure and mechanical properties of Mg97.5Gd1.9Zn0.6 alloy

open access: yesCailiao gongcheng, 2020
A ternary alloy strengthened by the phase with long period stacking ordered (LPSO) structure with composition of Mg97.5Gd1.9Zn0.6 (atom fraction/%) was prepared by conventional permanent mold casting.
ZHEN Rui   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

New weldable high strength aluminum alloy developed for cryogenic service [PDF]

open access: yes, 1966
Wrought aluminum alloy has improved low temperature notch toughness and weldability. This alloy can be mill-fabricated to plate and sheet without difficulty. Post-weld aging improves weld ductility and strength properties.

core   +1 more source

The potential therapeutic effects of creatine supplementation on body composition and muscle function in cancer [PDF]

open access: yes, 2018
Low muscle mass in individuals with cancer has a profound impact on quality of life and independence and is associated with greater treatment toxicity and poorer prognosis.
Fairman, C M   +5 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Effect of heat treatment on cracks and properties of self-piercing riveted joint in aluminum alloy

open access: yesHanjie xuebao
By considering the influence of cracks in self-piercing riveted joints of aluminum alloys on the static mechanical properties, an annealing process was applied to heat-treat 2024 aluminum alloy base plates before riveting.
Yanfen YANG   +4 more
doaj   +1 more source

Selective Laser-Melted Alloy 625: Optimization of Stress-Relieving and Aging Treatments

open access: yesApplied Sciences
Additive manufacturing is an innovative solution to produce components characterized by complex geometries. The use of such parts requires a deep knowledge of their behavior under different service conditions, especially from mechanical and corrosion ...
Barbara Rivolta   +2 more
doaj   +1 more source

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