Results 101 to 110 of about 21,307 (186)

An Autochthonous Case of Echinococcus vogeli Rausch & Bernstein, 1972 Polycystic Echinococcosis in the State of Rondônia, Brazil

open access: yesMemorias do Instituto Oswaldo Cruz, 2002
The present case report refers to a patient from the State of Rondônia, North region of Brazil, attended with clinical suspicion of hepatic echinococcosis.
Rosângela Rodrigues-Silva   +4 more
doaj   +1 more source

The alpaca agouti gene: Genomic locus, transcripts and causative mutations of eumelanic and pheomelanic coat color [PDF]

open access: yes, 2013
The agouti gene encodes the agouti signaling protein (ASIP) which regulates pheomelanin and eumelanin synthesis in mammals. To investigate the role of agouti in coat color variation of alpaca, we characterized the agouti gene and identified three ...
LA TERZA, Antonietta   +3 more
core   +1 more source

The evidence of metabolic-improving effect of metformin in Ay/a mice with genetically-induced melanocortin obesity and the contribution of hypothalamic mechanisms to this effect.

open access: yesPLoS ONE, 2019
In diet-induced obesity, metformin (MF) has weight-lowering effect and improves glucose homeostasis and insulin sensitivity. However, there is no information on the efficiency of MF and the mechanisms of its action in melanocortin-type obesity.
Kira Derkach   +6 more
doaj   +1 more source

Epigenome modulated xenobiotic detoxification pathways control DMBA-induced breast cancer in agouti Avy/a mice

open access: yesEpigenetics, 2019
Environmental xenobiotics with genotoxic activity are carcinogenic. However, individual differences in the susceptibility to xenobiotic-induced breast cancer remain unclear. Since epigenetic modifications could control the expression of metabolic enzymes,
Simbarashe Mazambani   +2 more
doaj   +1 more source

Molecular analysis of the mouse agouti gene and the role of dominant agouti-locus mutations in obesity and insulin resistance

open access: yes, 1994
The lethal yellow (A{sup y/-}) and viable yellow (A{sup vy/-}) mouse agouti mutants have a predominantly yellow pelage and display a complex syndrome that includes obesity, hyperinsulinemia, and insulin resistance, hallmark features of obesity-associated
Woychik, R. P.   +2 more
core  

Mechanisms of agouti-induced obesity : effects on adipocyte metabolism and interaction with insulin [PDF]

open access: yes, 1999
Dominant mutations at the agouti locus such as viable yellow (Avy) cause a syndrome of marked obesity and diabetes in addition to a characteristic yellow coat color.
Claycombe, Kate J.
core  

Agouti modulation of both adipocyte and pancreatic islet function via a Ca²⁺-dependent mechanism [PDF]

open access: yes, 2000
Dominant mutations at the promoter of the mouse agouti gene results in a yellow coat color as well as obesity, hyperinsulinemia, insulin resistance and gender-dependent hyperglycemia.
Xue, Bingzhong
core  

Gene structure of the goldfish agouti-signaling protein: A putative role in the dorsal-ventral pigment pattern of fish

open access: yes, 2005
One of the most successful chromatic adaptations in vertebrates is the dorsal-ventral pigment pattern in which the dorsal skin is darkly colored, whereas the ventrum is light.
Schioth, H.B.   +3 more
core   +1 more source

Analysis of the function of the agouti gene in obesity and diabetes [PDF]

open access: yes, 1996
This chapter discusses the agouti gene and dominant mutations in that gene that lead to agouti-induced obesity, and recent work with transgenic mice to elucidate the role of agouti in obesity.
Miltenberger, R. J.   +2 more
core  

Agouti paca

open access: yes, 1982
Agouti paca (Linnaeus, 1766). Syst. Nat., 12th ed., 1:81. REVIEWED BY: J. Ramirez-Pulido (JRP). TYPE LOCALITY: French Guiana, Cayenne. DISTRIBUTION: S.E. San Luis Potosi (Mexico) to Paraguay, Guianas, and S. Brazil. Introduced into Cuba (CAW). ISIS
Kenneth E. Kinman   +2 more
core   +1 more source

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