Results 181 to 190 of about 315,422 (280)

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Male Infertility Management: A Critical Appraisal of Clinical Practice Guidelines With the AGREE II Instrument. [PDF]

Am J Mens Health
Li J, Li K, Zhang M, Chen J, Chen M, Dong W, Yu W, Lei L, Huang Y, Yang H, Ren P, Zou Q, Deng L.   +12 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Quality Assessment of the European Association of Urology Guidelines Using the AGREE II Tool. [PDF]

Eur Urol Open Sci
Sakalis V, Omar MI, Conroy L, MacLennan S, Marconi L, Nambiar A, Rai B, Schouten N, Smith EJ, Smith CT, Yuan Y, Ribal M, Canfield S.   +12 more
europepmc   +1 more source

Complementary and alternative medicine mention and recommendations in inflammatory bowel disease guidelines: systematic review and assessment using AGREE II. [PDF]

BMC Complement Med Ther, 2023
Ng JY, Liu H, Wang MC.
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Management of Head and Neck Paragangliomas: AGREE II Appraisal of Clinical Practice Guidelines. [PDF]

Ann Surg Oncol
Lakshmipathy DR, Winter E, Fritz C, Balar O, Prasad A, Moreira A, Rajasekaran K.   +6 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Erratum to "World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) Guidelines update - IV - A quality appraisal with the AGREE II instrument" [World Allergy Organ J 15(2) (February 2022) 100613]. [PDF]

World Allergy Organ J
Strózyk A, Ruszczynski M, Horvath A, Dahdah L, Fiocchi A, Nowak-Węgrzyn A, Shamir R, Spergel J, Vandenplas Y, Venter C, Szajewska H, WAO DRACMA guideline group.   +11 more
europepmc   +1 more source

Quality and Content Concordance of International Clinical Guidelines on Hypertensive Disorders of Pregnancy Using the AGREE II Instrument: An Updated Systematic Review. [PDF]

J Cardiovasc Dev Dis, 2023
Bazzano AN, Keenan A, Woltz S, Subramanian A, Akpogheneta O, Coronado Daza J, Bazzano LAL.   +6 more
europepmc   +1 more source