Results 61 to 70 of about 52,487 (253)

Median scores of evaluated guidelines in five domains of AGREE II instrument.

, 2013
Median scores of evaluated guidelines in five domains of AGREE II instrument.
Petra Nimac Kozina (435173), Katarina Ivana Tudor (435172), Ana Marušić (109455)   +2 more
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Quality appraisal of clinical practice guidelines for the management of Dysphagia after acute stroke

Frontiers in Neurology, 2023
ObjectivesDysphagia is a common complication in stroke patients, widely affecting recovery and quality of life after stroke. The objective of this systematic review is to identify the gaps that between evidence and practice by critically assessing the ...
Shi-Lin Gao, Chang-Qing Liu, Qing-Hua Han, Xiao-Rong Dai, Yi-Wen Liu, Ka Li   +5 more
doaj   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Assessing the methodological quality of clinical guidelines for preventing falls of patients

Central European Journal of Nursing and Midwifery, 2016
Aim: The study aimed to assess the methodological quality of selected clinical practice guidelines (CPGs) for preventing risk of falling in adult patients in acute and long-term institutional care.
Kamila Majkusová, Darja Jarošová, Renáta Zeleníková, Radka Kozáková   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Appraisal of the “pediatric ARDS: Consensus recommendations from the pediatric acute lung injury consensus conference” with the AGREE II instrument

, 2018
PubMedID: 29479961Background/aim: The “Pediatric Acute Lung Injury Consensus Conference” (PALICC) was convened in order to develop a taxonomy to define pediatric acute respiratory distress syndrome (ARDS).
Yildizdaş R.D., Çelik Ü., Çelik T., Tolunay İ., Tolunay O.   +4 more
core   +2 more sources

Guidelines in cardiac clinical practice: evaluation of their methodological quality using the AGREE II instrument [PDF]

Journal of the Royal Society of Medicine, 2013
Although clinical guidelines have an influential role in healthcare practice, their development process and the evidence they cite has been subject to criticism. This study evaluates the quality of guidelines in cardiac clinical practice by examining how they adhere to validated methodological standards in guideline development.
Sanjeeve, Sabharwal, Vanash, Patel, Sukhjinder S, Nijjer, Ali, Kirresh, Ara, Darzi, John C, Chambers, Iqbal, Malik, Jaspal S, Kooner, Thanos, Athanasiou   +8 more
openaire   +2 more sources