Results 101 to 110 of about 2,442,342 (290)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Climate Change and Structural Emissions: Moral Obligations at the Individual Level [PDF]
, 2011 Given that mitigating climate change is a large-scale global issue, what obligations do individuals have to lower their personal carbon emissions? I survey recent suggestions by Walter Sinnott-Armstrong and Dale Jamieson and offer models for thinking ...
Aufrecht, Monica
core
On the validity of the guiding-center approximation in the presence of strong magnetic gradients
, 2017 The motion of a charged particle in a nonuniform straight magnetic field with a uniform magnetic-field gradient is solved exactly in terms of elliptic functions. The connection between this problem and the guiding-center approximation is discussed. It is
Brizard, Alain J.
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
BMC ChemistryIn this work, a new, sensitive, precise, accurate, and eco-friendly spectrofluorometric method for the detection of Bosentan in human plasma and pharmaceutical dosage form was developed, using silver nanoparticles (AgNPs) as an efficient fluorescence ...
Yossra A. Trabik +3 more
doaj +1 more source
Green Analytical ChemistryThis study aims to develop and validate novel UV spectrophotometric methods for the simultaneous estimation of atenolol and hydrochlorothiazide in pharmaceutical dosage forms and bulk. The proposed methods are Simultaneous Equation and Q-Absorbance Ratio
Ashok H. Akabari +7 more
doaj +1 more source
Fluctuations of large-scale jets in the stochastic 2D Euler equation [PDF]
, 2016 Two-dimensional turbulence in a rectangular domain self-organises into large-scale unidirectional jets. While several results are present to characterize the mean jets velocity profile, much less is known about the fluctuations. We study jets dynamics in
Nardini, Cesare, Tangarife, Tomás
core +2 more sources
A C-13(alpha,n)O-16 calibration source for KamLAND
, 2008 We report on the construction and performance of a calibration source for KamLAND using the reaction C-13(alpha,n)O-16 with Po-210 as the alpha progenitor.
Araki +11 more
core +1 more source
Quality & QuantityAbstractA methodologically important area in political science is measuring the ideology of voters. This task can be difficult, and researchers often rely on ‘off the shelf’ datasets. Many of these datasets contain unbalanced Likert scales, which risk acquiescence bias. This paper proposes a strategy for dealing with this issue.
openaire +2 more sources
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source