Results 61 to 70 of about 40,282 (258)

Proximity and Same Case Marking Do Not Increase Attraction Effect in Comprehension: Evidence From Eye-Tracking Experiments in Korean

open access: yesFrontiers in Psychology, 2019
Previous studies have suggested that during the on-line sentence processing, relevant memory representations are directly accessed based on cues at retrieval (McElree et al., 2003). Under this hypothesis, retrieval cues activate any memory representation
Nayoung Kwon, Patrick Sturt
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Task-dependency and structure-dependency in number interference effects in sentence comprehension

open access: yesFrontiers in Psychology, 2015
We report three experiments on French that explore number mismatch effects in intervention configurations in the comprehension of object A’-dependencies, relative clauses and questions.
Julie eFranck   +3 more
doaj   +1 more source

Electrostatically assisted macroion association

open access: yesCondensed Matter Physics, 2021
A model system of highly asymmetric polyelectrolyte with directional short-range attractive interactions was studied by canonical Monte Carlo computer simulations.
J. Reščiš
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Number and Grammatical Gender Attraction in Spanish Pronouns: Evidence for a Syntactic Route to Their Features

open access: yesJournal of Cognition
When a speaker produces a pronoun, they must choose a form that carries the appropriate features. The current study investigates how speakers identify these features.
Margaret Kandel   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Persistent meanders and eddies lead to quasi-steady Lagrangian transport patterns in a weak western boundary current

open access: yesScientific Reports, 2021
The Brazil Current (BC) is a weak western boundary current flowing along the Southwestern Atlantic Ocean. It is frequently described as a flow with intense mesoscale activity and relatively low volume transport between 5.0 and 10.0 Sv.
M. B. Gouveia   +6 more
doaj   +1 more source

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