Results 41 to 50 of about 3,934 (114)

Laminar CD34+ membranous cells with mechanosensitive properties in subcutaneous fascia of the abdominal midline

Scientific Reports
The study of soft, amorphous fascia has been constrained by definitional ambiguities regarding its fine structure, constituent and precise function. Here, a previously unrecognized CD34+ membranous cell (CMC) population was identified by single-cell RNA ...
Haixiang Huang, Lu Mei, Zhenwei Zhang, Jianming Yue, Meng Dai, Lu Lu, Min Yang, Lilin Fan, Tong Yang, Qiusheng Chen   +9 more
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Cytoskeleton disruption and plasma membrane damage determine methuosis of normal and malignant cells

Cell & Bioscience
Background Methuosis represents a novel cell death modality characterized by catastrophic cytoplasmic vacuolization in normal and malignant cells. However, the critical role and the underlying mechanism of cytoskeleton and plasma membrane damage in ...
Bin Dong, Jing Xiao, Junqi Wang, Xinhao Song, Hui Ji, Jiurong Peng, Xinru Weng, Dawei Guo, Shanxiang Jiang, Xiuge Gao   +9 more
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Neutrophil extracellular traps induced by Haemonchus contortus excretory–secretory proteins varies among goats, gerbils, and mice

Parasites & Vectors
Background Previous studies indicated that infection with Haemonchus contortus is host-specific (goat: susceptible host; gerbil: paratenic host; mouse: resistant host).
Yangchun Tan, Shuyi Cao, Muhammad Azhar Memon, Zhaohai Wen, Cheng Chen, Jiajun Feng, Xiaokai Song, Lixin Xu, Mingmin Lu, Ruofeng Yan   +9 more
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The ASFV CD2v protein inhibits apoptosis by inducing proteasomal degradation of BimEL via activation of the TPL2-MEK-ERK signaling pathway

Journal of Virology
African swine fever virus (ASFV) employs sophisticated regulatory strategies to manipulate host cell apoptosis, a process critical for its pathogenesis and immune evasion; however, the mechanisms underlying this process remain incompletely understood ...
Jianyu Zeng, Xin Zhang, Jingting Zhao, Qiang Li, Zhiyong Xiang, Fengyang Shi, Hua Wang, Wenlian Weng, Qiongqiong Zhou, Peng Gao, Lei Zhou, Xinna Ge, Jun Han, Xin Guo, Yongning Zhang, Hanchun Yang   +15 more
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Rumen microbiota modulates metabolic stress in high-yield dairy cows: insights from early to peak lactation

Microbiome
Background Early lactation (EL) in high-yield dairy cows represents a critical lactation phase marked by significant metabolic stress, which often provokes health disorders and production losses.
Moli Li, Shiquan Zhu, Huizeng Sun, Yihui Huo, Qiqi Cao, Zhaoju Deng, Kui Li, Yuxin He, Xiaojie Lu, Jian Gao, Chuang Xu   +10 more
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LIPOPHAGY: a novel form of steroidogenic activity within the LEYDIG cell during the reproductive cycle of turtle

Reproductive Biology and Endocrinology, 2019
Background Steroidogenesis is an indispensable process that is indirectly associated with spermatogenesis in the Leydig cell (LC) to utilize the lipid droplets (LDs) that are critical to maintaining normal testosterone synthesis.
Imran Tarique, Waseem Ali Vistro, Xuebing Bai, Ping Yang, Chen Hong, Yufei Huang, Abdul Haseeb, Enxue Liu, Noor Samad Gandahi, Mengdi Xu, Yifei Liu, Qiusheng Chen   +11 more
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A LXG toxin stabilized by DUF4176 contributes to Streptococcus suis competition and pathogenicity

BMC Biology
Background Streptococcus suis poses a significant threat to both humans and pigs, causing severe disease such as meningitis, septicaemia, and sudden death.
Huizhen Wu, Yifan Wu, Qiankun Bai, Zijing Liang, Xinchi Zhu, Xinming Pan, Minghui Liu, Huochun Yao, Jiale Ma, Zongfu Wu   +9 more
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Coronavirus infectious bronchitis virus spike protein inhibits FUNDC1-mediated mitophagy to prevent nucleocapsid protein degradation

Journal of Virology
Autophagy is involved in various stages of the viral life cycle and modulates viral replication. Coronaviruses have developed several strategies to exploit autophagy for their benefit.
Jun Zhao, Jiaxin Tian, Liwei Zhang, Yingfei Li, Lihua Tang, Qila Sa, Ruotong Li, Jing Zhao, Ye Zhao, Guozhong Zhang   +9 more
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Neuropeptide SP protects against colitis and linked anxiety-like behavior through the putative roles of gut microbiota and metabolite inositol

Nature Communications
The gut-brain axis links gut inflammation to psychiatric symptoms in inflammatory bowel disease (IBD), but the underlying mechanisms remain unclear. We demonstrate that neuropeptide substance P (SP) alleviated intestinal injury and behavioral disorders ...
Jing Lan, Jiaqi Wang, Sijuan Huang, Chenyu Li, Ziteng Deng, Zhihui Hao, Yunfei Ma   +6 more
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Role of nasal microbiota in regulating host anti-influenza immunity in dogs

Microbiome
Background Numerous studies have confirmed a close relationship between the pathogenicity of influenza and respiratory microbiota, but the mechanistic basis for this is poorly defined.
Jinzhu Geng, Yuhao Dong, Hao Huang, Xia Wen, Ting Xu, Yanbing Zhao, Yongjie Liu   +6 more
doaj   +1 more source