Results 61 to 70 of about 5,733,883 (336)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Megaproject on innovative transformation of the plant breeding system to increase productivity and yield (second half of the twentieth century)

open access: yesІсторія науки і техніки
The purpose of the article is to reconstruct the events and analyze the scientific activities of the geneticist Oleksii Sozinov (1930–2018) aimed at the development of agricultural science in Ukraine.
Svitlana Nyzhnyk
doaj   +1 more source

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

II International Congress of Mechanical Engineering and Agricultural Science (CIIMCA 2015)

open access: yes, 2016
The 2nd International congress of Mechanical Engineering and Agricultural Science (CIIMCA 2015) looked to exchange new scientific knowledge on mechanical engineering, agricultural science, materials science and related topics.

semanticscholar   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Thesaurus of Agricultural Sciences

open access: yes, 2010
This work is the Persian translation of the AROVOC thesaurus from February 2004, which covers the main scientific terms in various branches of agriculture (with 17,805 descriptors and 12,356 non-descriptors). Therefore, if it is properly utilized in Persian or Persian-English storage and retrieval systems, it can be quite effective.
Akbari, Esmaiel   +4 more
openaire   +1 more source

Gender Differences in Attitude towards the Learning of Agricultural Science in Senior High Schools in the Assin South District of the Central Region, Ghana

open access: yes, 2016
Agriculture has predominantly been observed as the activity of men with little or no interest by women hence this study was conducted in two public senior high schools in the Assin South district of the Central region of Ghana aimed to investigate gender
R. Darko   +5 more
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

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