Results 251 to 260 of about 2,360,658 (324)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

open access: yesAllergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter   +20 more
wiley   +1 more source

Patient‐reported outcomes, postoperative pain and pain relief after day‐case surgery (POPPY): baseline data from day surgery practice in the UK

open access: yesAnaesthesia, EarlyView.
Summary Introduction Most patients undergoing elective surgery in the UK are discharged from hospital on the same day. Despite this, there is a lack of UK patient‐centred outcome measures relating to quality of recovery, pain and analgesic use. The POPPY study was a UK‐wide prospective, observational study measuring short‐ and longer‐term patient ...
Martha Belete   +2177 more
wiley   +1 more source

Hemocompatibility Outcomes After Aspirin Withdrawal in Long‐Term HeartMate 3 Left Ventricular Assist Device Patients on Vitamin K Antagonists

open access: yesArtificial Organs, EarlyView.
Aspirin discontinuation in long‐term, stable Heart Mate 3 LVAD patients maintained on Vitamin K antagonists did not increase hemocompatibility‐related adverse events. These findings support the safety of simplified antithrombotic therapy and extend randomized evidence for aspirin avoidance to the long‐term management of Heart Mate 3 recipients ...
Melanie Arnreiter   +8 more
wiley   +1 more source

First Zoeal Stage of the Snapping Shrimp Alpheus Fabricius, 1798 (Caridea: Alpheidae): New Description of Alpheus bouvieri A. Milne‐Edwards, 1878 and Literature Review

open access: yesActa Zoologica, EarlyView.
ABSTRACT Based on adult morphological characters, the more than 300 species of Alpheus were divided into seven informal species groups, but some groups are not supported by molecular data. The aim here was to describe the zoea I of Alpheus bouvieri, and to do a review of the larval descriptions available in the literature, analysing whether the ...
Karmine Pasinatto   +2 more
wiley   +1 more source

Sustainability in Healthcare: The Role of Digital Technologies for Improving Patient Engagement

open access: yesBusiness Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Sustainability in healthcare is getting considerable research attention as systems worldwide tend to balance environmental, social, and economic factors. In this context, digital technologies have demonstrated significant potential to enhance engagement among different consumer groups across various industries.
Francesco Schiavone   +4 more
wiley   +1 more source

A Farewell to Arms… Manufacturing: Learning From a Landmine Producer Who Became a Deminer

open access: yesBusiness Ethics, the Environment &Responsibility, EarlyView.
ABSTRACT Certain industries—labeled “dirty,” “sinful,” “stigmatized,” or “controversial”—are under public scrutiny because of the ethical, social, and environmental concerns that they raise. Previous research has typically focused on the industry or organizational level of analysis, examining how companies in controversial industries can enhance their ...
Marco Guerci, Luca Carollo
wiley   +1 more source

Feasibility and workflow analysis of confocal microscopy in robot‐assisted prostatectomy

open access: yesBJU International, EarlyView.
Objectives To assess the diagnostic accuracy, workflow feasibility, and downstream compatibility of fluorescence confocal microscopy (Histolog® Scanner [HS]; SamanTree Medical SA, Lausanne, Switzerland) compared with frozen section (FS) for intraoperative margin evaluation (IME) during nerve‐sparing robot‐assisted radical prostatectomy (RARP). Patients
Kristijan Skok   +11 more
wiley   +1 more source

SUSD2 Promotes Metastasis and Primary Tumor Growth in Pancreatic Cancer Cells via Integrin–FAK Signaling Activation

open access: yesCancer Science, EarlyView.
This study investigates the role of Sushi domain‐containing 2 (SUSD2) in pancreatic ductal adenocarcinoma (PDAC) and demonstrates that SUSD2 enhances both metastasis and primary tumor growth by promoting integrin β1–FAK signaling. SUSD2 interacts with integrin β1, enhancing adhesion to extracellular matrix (ECM) components such as collagen 1 and ...
Junjiro Yoshida   +11 more
wiley   +1 more source

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