Results 81 to 90 of about 80,990 (290)

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

Major Changes in the 2005 AHA Guidelines for CPR and ECC [PDF]

open access: bronze, 2005
Mary Fran Hazinski   +5 more
openalex   +1 more source

2020 AHA/ACC Guideline for the Diagnosis and Treatment of Patients With Hypertrophic Cardiomyopathy: Executive Summary [PDF]

open access: bronze, 2020
Steve R. Ommen   +18 more
openalex   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher   +12 more
wiley   +1 more source

ACC/AHA Key Data Elements and Definitions for Measuring the Clinical Management and Outcomes of Patients With Atrial Fibrillation [PDF]

open access: bronze, 2004
Robert L. McNamara   +19 more
openalex   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Clinical Significance of the Detection of Antinuclear Antibodies in Patients with Acute Hepatitis A

open access: yesGut and Liver, 2011
Background/AimsThe findings of several recent studies suggest that antinuclear antibodies (ANAs) are frequently detected in patients with acute hepatitis A (AHA). However, the clinical significance of a positive ANA test remains uncertain. This study was
doaj   +1 more source

A Program‐Led Motivational App (MI‐Coach: ED) for Eating Disorder Waitlists: Findings From a Feasibility and Acceptability Pilot Trial

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Individuals with eating disorders (EDs) often face significant barriers to accessing care, including prolonged waitlists and systemic delays. Digital interventions, such as mobile apps, offer a scalable way to enhance pre‐treatment engagement during this high‐risk period.
Amané Halicki‐Asakawa   +2 more
wiley   +1 more source

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