Results 31 to 40 of about 21,014 (227)

Molecular genetic and mitochondrial metabolic analyses confirm the suspected mitochondrial etiology in a pediatric patient with an atypical form of alternating hemiplegia of childhood

Molecular Genetics and Metabolism Reports, 2020
Alternative hemiplegia of childhood (AHC) is a rare neurodevelopmental disorder with an extensive phenotypic variability, resulting in a challenging clinical diagnosis.
Andrea Gropman, Martine Uittenbogaard, Christine A. Brantner, Yue Wang, Lee-Jun Wong, Anne Chiaramello   +5 more
doaj   +1 more source

Molecular Characterization and Phylogenetic Study of Coxsackievirus A24v Causing Outbreaks of Acute Hemorrhagic Conjunctivitis (AHC) in Brazil

PLoS ONE, 2011
Background Coxsackievirus A24 variant (CA24v) is the most prevalent viral pathogen associated with acute hemorrhagic conjunctivitis (AHC) outbreaks.
F. N. Tavares, R. de Mendonça Campos, F. Burlandy, Rachel Fontella, M. M. M. de Melo, E. V. da Costa, E. D. da Silva   +6 more
semanticscholar   +1 more source

Increase in consumption of alcohol-based hand rub in German acute care hospitals over a 12 year period

BMC Infectious Diseases, 2021
Background Hand hygiene plays a crucial role in the transmission of pathogens and the prevention of healthcare-associated infections. In 2007, a voluntary national electronic surveillance tool for the documentation of consumption of alcohol-based hand ...
Tobias Siegfried Kramer, Janine Walter, Christin Schröder, Michael Behnke, Jörg Clausmeyer, Christiane Reichardt, Petra Gastmeier, Karin Bunte   +7 more
doaj   +1 more source

Developing and Evaluating a Quality Improvement Intervention to Facilitate Patient Navigation in the Accountable Health Communities Model

Frontiers in Medicine, 2021
Introduction: The Accountable Health Communities (AHC) Model was designed to address the health-related social needs of Centers for Medicare & Medicaid Services beneficiaries.
Jennifer L. Holcomb, Gretchen H. Walton, Itunu O. Sokale, Gayla M. Ferguson, Vanessa R. Schick, Linda Highfield, Linda Highfield, Linda Highfield   +7 more
doaj   +1 more source

After-Hours Care in Suburban Canada

Journal of Primary Care & Community Health, 2011
Objective : To determine if operation of an outpatient “after-hours” clinic (AHC) was associated with a reduction in local emergency department (ED) visits. Study Setting : Leduc, Alberta, Canada is a city of approximately 20 000 people.
David Jones MSc, Linda Carroll PhD, Leonard Frank MSc   +2 more
doaj   +1 more source

Deterministic Local Interpretable Model-Agnostic Explanations for Stable Explainability

Machine Learning and Knowledge Extraction, 2021
Local Interpretable Model-Agnostic Explanations (LIME) is a popular technique used to increase the interpretability and explainability of black box Machine Learning (ML) algorithms.
Muhammad Rehman Zafar, N. Khan
semanticscholar   +1 more source

Observation of Magnetic‐Anisotropy Crossover and High‐Temperature Skyrmions in the Dirac Magnet Fe3Ge with a Distorted Kagome Lattice

Advanced Science, EarlyView.
A temperature‐driven magnetic anisotropy crossover is revealed in the Dirac kagome magnet Fe3Ge with a distorted kagome lattice. The transition from easy‐plane to easy‐axis magnetic anisotropy stabilizes robust Bloch‐type skyrmions over an exceptionally wide temperature window of 375–650 K.
Yalei Huang, Xiaowei Lv, Bin Li, Chunqiang Xu, Dhanarajagopal Alltrin, Xiaoxuan Ma, Wanting Yang, Wei Zhou, Xiangzhuo Xing, Wen‐Chin Lin, Raman Sankar, Michael Smidman, Shixun Cao, Dong Qian, Renchao Che, Xiaofeng Xu   +15 more
wiley   +1 more source

HIV Vaccine: Recent Advances, Current Roadblocks, and Future Directions

Journal of Immunology Research, 2015
HIV/AIDS is a leading cause of mortality and morbidity worldwide. In spite of successful interventions and treatment protocols, an HIV vaccine would be the ultimate prevention and control strategy.
Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Nancy Shehadeh, Sandeep Appunni   +4 more
doaj   +1 more source

Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice.

PLoS ONE, 2013
Missense mutations in ATP1A3 encoding Na(+),K(+)-ATPase α3 have been identified as the primary cause of alternating hemiplegia of childhood (AHC), a motor disorder with onset typically before the age of 6 months.
Greer S Kirshenbaum, Neil Dawson, Jonathan G L Mullins, Tom H Johnston, Mark J Drinkhill, Ian J Edwards, Susan H Fox, Judith A Pratt, Jonathan M Brotchie, John C Roder, Steven J Clapcote   +10 more
doaj   +1 more source

Neuronal modeling of alternating hemiplegia of childhood reveals transcriptional compensation and replicates a trigger-induced phenotype

Neurobiology of Disease, 2020
Alternating hemiplegia of childhood (AHC) is a rare neurodevelopmental disease caused by heterozygous de novo missense mutations in the ATP1A3 gene that encodes the neuronal specific α3 subunit of the Na,K-ATPase (NKA) pump. Mechanisms underlying patient
John P. Snow, Grant Westlake, Lindsay K. Klofas, Soyoun Jeon, Laura C. Armstrong, Kathryn J. Swoboda, Alfred L. George, Jr, Kevin C. Ess   +7 more
doaj   +1 more source