Results 1 to 10 of about 165,991,670 (135)

Oral ATP treatment in alternating hemiplegia of childhood: a case report and review [PDF]

Frontiers in Medicine
Alternating hemiplegia of childhood (AHC) is a rare neurological disorder that usually manifests before 18 months of age and is characterized by recurrent, alternating episodes of hemiparesis with variable frequency and can last from a few minutes to ...
Marco Carrozzi, Maria Elisa Morelli, Mario Cirino, Alessandra Maestro, Gilda Paternuosto, Giulia Benericetti, Giada Bennati, Maura Bin, Anna Flamigni, Federico Pigato, Natalia Maximova, Egidio Barbi, Egidio Barbi, Davide Zanon   +13 more
doaj   +4 more sources

Alternating hemiplegia of childhood: An electroclinical study of sleep and hemiplegia. [PDF]

PLoS ONE, 2022
ObjectiveAlternating Hemiplegia of Childhood (AHC) is characterised by paroxysmal hemiplegic episodes and seizures. Remission of hemiplegia upon sleep is a clinical diagnostic feature of AHC.
Josephine Poole, Sara Zagaglia, Rita Demurtas, Fiona Farrell, Matthew C Walker, Sanjay M Sisodiya, Simona Balestrini, Umesh Vivekananda   +7 more
doaj   +4 more sources

Alternating Hemiplegia of Childhood: neurological comorbidities and intrafamilial variability [PDF]

Italian Journal of Pediatrics, 2022
Background Alternating of Childhood (AHC) is an uncommon and complex disorder characterized by age of onset before 18 months with recurrent hemiplegia of one or either sides of the body or quadriplegia.
Piero Pavone, Xena Giada Pappalardo, Naira Mustafa, Sung Yoon Cho, Dong Kyu Jin, Gemma Incorpora, Raffaele Falsaperla, Simona Domenica Marino, Giovanni Corsello, Enrico Parano, Martino Ruggieri   +10 more
doaj   +2 more sources

Alternating Hemiplegia of Childhood: Genotype–Phenotype Correlations in a Cohort of 39 Italian Patients [PDF]

Frontiers in Neurology, 2021
Alternating hemiplegia of childhood is a rare neurological disease characterized by paroxysmal movement disorders and chronic neurological disturbances, with onset before 18 months of age. Mutations in the ATP1A3 gene have been identified in up to 80% of
Ramona Cordani, Michela Stagnaro, Livia Pisciotta, Livia Pisciotta, Francesco Danilo Tiziano, Maria Grazia Calevo, Lino Nobili, Lino Nobili, I.B.AHC Consortium, Elisa De Grandis, Elisa De Grandis   +10 more
doaj   +2 more sources

De novo ATP1A2 variants in two Chinese children with alternating hemiplegia of childhood upgraded the gene–disease relationship and variant classification: a case report [PDF]

BMC Medical Genomics, 2021
Background ATP1A2 gene mutation has been indicated to cause alternating hemiplegia of childhood (AHC); however, limited evidence supports this relationship so far.
Danping Huang, Min Liu, Hongying Wang, Bingbing Zhang, Dongjing Zhao, Weihao Ling, Manli Wang, Jun Feng, Yiping Shen, Xuqin Chen   +9 more
doaj   +2 more sources

Effect of Flunarizine on Alternating Hemiplegia of Childhood in a Patient with the p.E815K Mutation in ATP1A3: A Case Report [PDF]

Case Reports in Neurology, 2020
Alternating hemiplegia of childhood (AHC) (MIM 104290) is characterized by transient repeated attacks of paresis on either or both sides of the body, oculomotor and autonomic abnormalities, movement disorders, and cognitive impairment.
Shouichirou Kusunoki, Jun Kido, Ken Momosaki, Takaaki Sawada, Tomoko Kashiki, Shirou Matsumoto, Kimitoshi Nakamura   +6 more
doaj   +2 more sources

RHOBTB2-Associated Neurological Phenotypes and Underlying Mechanisms: Alternating Hemiplegia of Childhood Beyond ATP1A3 [PDF]

Diseases
Alternating hemiplegia of childhood (AHC) represents a severe and complex pediatric neurodevelopmental disorder, predominantly characterized by the occurrence of paroxysmal episodes of transient unilateral or bilateral paresis prior to 18 months of age ...
Ruzica Kravljanac, Kristel Klaassen, Vladimir Oparnica, Biljana Vucetic Tadic, Marina Andjelkovic, Anita Skakic, Sara Stankovic, Maja Stojiljkovic   +7 more
doaj   +2 more sources

Alternating Hemiplegia of Childhood: gastrointestinal manifestations and correlation with neurological impairments [PDF]

Orphanet Journal of Rare Diseases, 2020
Background Alternating Hemiplegia of Childhood (AHC) is caused by mutations of the ATP1A3 gene which is expressed in brain areas that include structures controling autonomic, gastrointestinal, gut motility and GABAergic functions. We aimed to investigate,
Milton Pratt, Julie Uchitel, Nancy McGreal, Kelly Gordon, Lyndsey Prange, Melissa McLean, Richard J. Noel, Blaire Rikard, Mary K. Rogers Boruta, Mohamad A. Mikati   +9 more
doaj   +2 more sources

Clinical Improvement in a Case of Alternating Hemiplegia of Childhood After Cerebral Lymphatic Drainage [PDF]

International Medical Case Reports Journal
Sandro Mandolesi,1 Tarcisio Niglio,2 Michela Stagnaro,3 Elisa De Grandis3 1Research Department of the Mediterranean Pole, Technoscience, Science and Technology Park, San Severo, Italy; 2Department of Knowledge and Scientific Communication, Istituto ...
Mandolesi S, Niglio T, Stagnaro M, De Grandis E   +3 more
doaj   +2 more sources

Navigating the Complexity of Alternating Hemiplegia in Childhood: A Comprehensive Review [PDF]

Rambam Maimonides Medical Journal
Alternating hemiplegia of childhood (AHC) is a complex neurodevelopmental disorder characterized by paroxysmal and transient events of unilateral or bilateral paresis, usually occurring before 18 months of age.
Jamir Pitton Rissardo, Nilofar Murtaza Vora, Yogendra Singh, Sweta Kishore, Ana Letícia Fornari Caprara   +4 more
doaj   +2 more sources