Synthesis and analysis of stable isotope-labelled N-acyl homoserine lactones [PDF]
, 2016 Aliphatic aldehydes were deuterated at the alpha-position via a base-catalyzed exchange reaction with D2O. These deuterated building blocks were used for the synthesis of labelled analogues of quorum sensing signal molecules belonging to the three major ...
De Kimpe, Norbert +3 more
core +2 more sources
A population-based microbial oscillator [PDF]
, 2010 Genetic oscillators are a major theme of interest in the emerging field of synthetic biology. Until recently, most work has been carried out using intra-cellular oscillators, but this approach restricts the broader applicability of such systems ...
Amos, Martyn, Goni-Moreno, Angel
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Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]
, 2008 Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
A Bultreys +38 more
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Quorum-quenching activity of the AHL-lactonase from Bacillus licheniformis DAHB1 inhibits vibrio biofilm formation in vitro and reduces shrimp intestinal colonisation and mortality [PDF]
, 2014 Vibrio parahaemolyticus is a significant cause of gastroenteritis resulting from the consumption of undercooked sea foods and often cause significant infections in shrimp aquaculture. Vibrio virulence is associated with biofilm formation and is regulated
Shanthi, S. +4 more
core +3 more sources
Chemical communication between synthetic and natural cells: a possible experimental design [PDF]
, 2013 The bottom-up construction of synthetic cells is one of the most intriguing and interesting research arenas in synthetic biology. Synthetic cells are built by encapsulating biomolecules inside lipid vesicles (liposomes), allowing the synthesis of one or ...
D'Angelo, Francesca +5 more
core +3 more sources
Frontiers in Cellular and Infection Microbiology, 2018 N-Acyl Homoserine Lactones (N-AHLs) are an important group of small quorum-sensing molecules generated and released into the surroundings by Gram-negative bacteria.
Jianfei Liu +5 more
doaj +1 more source
Social interactions in the Burkholderia cepacia complex : biofilms and quorum sensing [PDF]
, 2010 Burkholderia cepacia complex bacteria are opportunistic pathogens that cause respiratory tract infections in susceptible patients, mainly people with cystic fibrosis. There is convincing evidence that B.
Coenye, Tom
core +2 more sources
Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction [PDF]
, 2011 BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection.
Fang, K. +9 more
core +2 more sources
The diversity of AHLs in WWTPs needs to be assessed more rigorously
Chemical Engineering Journal Advances, 2022 Quorum sensing (QS) plays a vital role in multiple species' inter-communication in man-made ecosystems, especially in bioaugmentation technologies. The role of various acyl-homoserine lactone (AHL), especially thirteen AHL types mediated QS in bacterial ...
Hongxin Mu +7 more
doaj +1 more source
Frontiers in Microbiology, 2019 Some bacteria can modulate their spoilage potential by responding to environmental signaling molecules via the quorum sensing (QS) system. However, the ability of Pseudomonas fluorescens, the specific spoilage organism (SSO) of turbot, to response to ...
Tingting Li +8 more
doaj +1 more source