Results 201 to 210 of about 12,784 (283)

Surgical Timing and Survival in Advanced High-Grade Serous Ovarian Cancer in the PARP Inhibitor Era. [PDF]

Cancers (Basel)
Kanno M, Fusegi A, Miyazaki N, Ozawa R, Netsu S, Aoki Y, Omi M, Nomura H, Yunokawa M, Kanao H.   +9 more
europepmc   +1 more source

Characterisation and Prognostic Implication of Cholestasis After Burn Injury

Alimentary Pharmacology &Therapeutics, EarlyView.
In 532 burn ICU patients, we quantified trajectories of cholestasis markers and validated burn‐associated cholestasis definitions. Bilirubin dynamics, particularly hyperbilirubinemia ≥ 2× ULN within 14 days, independently predicted excess in‐hospital and overall mortality beyond burn and critical‐illness severity, identifying a high‐risk subgroup after
Lorenz Semmler, Georg Semmler, Andreas Langa, Sebastian Rihl, Sebastian Hofstetter, Melissa‐Patricia Mateas, Kevin Dilmen, Anton Borger, Paul Supper, Patrick Haselwanter, Emina Halilbasic, Christian Zauner, Albert Stättermayer, Gerald Ihra, Christine Radtke, Mathias Anselm Schneeweiss‐Gleixner, Michael Trauner   +16 more
wiley   +1 more source

AHR activation by uraemic solutes [PDF]

Nature Reviews Nephrology, 2019
openaire   +2 more sources

Inequalities in breast cancer incidence and mortality in women with and without disabilities in South Korea: A population-based cohort study. [PDF]

Prev Med Rep
Kang HY, Park E, Bui TT, Kim B, Oh JK.
europepmc   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

The impact of religiosity, anxiety and depression on proneness to auditory hallucinations in healthy individuals. [PDF]

BJPsych Open
Lucafò C, Ceccato I, Malatesta G, Palumbo R, Mammarella N, Di Domenico A, Tommasi L, Prete G.   +7 more
europepmc   +1 more source

Increasing Filamins A and B in Th2 Lymphocytes as a Therapeutic Opportunity to Attenuate Airway Inflammation in Mice

Allergy, EarlyView.
Léa Chamy, Kilian Maire, Charlotte Hateb, Arun Subramaniam, Safia Deddouche‐Grass, Laurent L. Reber, Pierre G. Lutz, Isabelle Lamsoul   +7 more
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

British Journal of Pharmacology, EarlyView.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam, Smriti Sharma, Gregor Aitchison, Ayman Gebril, Ioannis Stasinopoulos, Sofia Laforest, Chelbi Coyle, Ruth Andrew, Natalie Z. M. Homer, Sébastien Bonnet, Sandra Breuils‐Bonnet, Martin Wabitsch, Margaret R. MacLean   +12 more
wiley   +1 more source

Age-stratified Associations between Chronic Periodontal Disease and Clinical Outcomes in Hemodialysis Patients: Mortality, Pneumonia, and Fractures. [PDF]

Int J Med Sci
Liao MT, Lu CL, Huang RY, Wang J, Zheng CM, Hou YC, Tai CY, Lu KC.   +7 more
europepmc   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, EarlyView.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source