Results 271 to 280 of about 98,954,750 (292)

Boron Binding with the Quorum Sensing Signal AI-2 and Analogues

Organic Letters, 2004
[reaction: see text] The unstable bacterial metabolic product, DPD, and the related natural product, laurencione, are shown to have a high affinity for borate complexation, through the hydrated analogue. The boron complex of DPD is Vibrio harveyi AI-2, an interspecies quorum sensing signal in bacteria, and an affinity column with a borate resin is ...
Martin F, Semmelhack, Shawn R, Campagna, Charlotte, Hwa, Michael J, Federle, Bonnie L, Bassler   +4 more
openaire   +2 more sources

Ozonolysis of Alkynes—A Flexible Route to Alpha-Diketones: Synthesis of AI-2

Organic Letters, 2020
A mild procedure for the low-temperature conversion of alkynes to diketones has been developed and employed in the synthesis of AI-2.
Joshua L. Alterman, Dua X. Vang, Marissa Roghair Stroud, Larry J. Halverson, George A. Kraus   +4 more
openaire   +2 more sources

(AI)2 Artificially Intelligent Artifact Interpreter

2011
This project prototypes a virtual history museum docent to interpret historical artifacts to a general audience. Engaging visitors in exploring original artifacts is the key to successfully connecting them to human history. Traditionally artifacts have been presented in two ways.
Pershey, Edward J., Pershey, Edward J.
openaire   +1 more source

amor ais 2

2023
Entre 2006 e 2011 Francisco Providência teve presença diária na secção de opinião do Jornal de Notícias, ilustrando os textos dos seus convidados. Essas ilustrações, realizadas no limite da escassez de meios a esferográfica sobre papel A4, eram produzidas sob a tensão da corrida contra o tempo, muitas vezes em breves minutos e posteriormente enviadas ...
openaire   +1 more source

Biological screening of a diverse set of AI-2 analogues in Vibrio harveyi suggests that receptors which are involved in synergistic agonism of AI-2 and analogues are promiscuous

Chemical Communications, 2009
C1-alkyl AI-2 analogues do not induce bioluminescence in V. harveyi on their own but enhance the bioluminescence induced by AI-2 in a synergistic fashion. A new facile synthesis of AI-2 facilitates the synthesis of a diverse set of AI-2 analogues and biological screening suggests that receptors that are involved in the synergistic bioluminescence ...
Jacqueline A I, Smith, Jingxin, Wang, Sao-Mai, Nguyen-Mau, Vincent, Lee, Herman O, Sintim   +4 more
openaire   +2 more sources

AI-2 analogs and antibiotics: a synergistic approach to reduce bacterial biofilms

Applied Microbiology and Biotechnology, 2012
Quorum sensing (QS), the process of autoinducer-mediated cell-cell signaling among bacteria, facilitates biofilm formation, virulence, and many other multicellular phenotypes. QS inhibitors are being investigated as antimicrobials because of their potential to reduce symptoms of infectious disease while slowing the emergence of resistant strains ...
Varnika, Roy, Mariana T, Meyer, Jacqueline A I, Smith, Sonja, Gamby, Herman O, Sintim, Reza, Ghodssi, William E, Bentley   +6 more
openaire   +2 more sources

Detection of Autoinducer (AI-2)-Like Activity in Food Samples

2010
The contamination, survival, and possible foodborne disease outbreaks are major issues confronting the food industry. However, from a microbial perspective, any food whether natural or processed is just another environmental niche that is available for colonization.
Kirthiram K, Sivakumar, Palmy R, Jesudhasan, Suresh D, Pillai   +2 more
openaire   +2 more sources

AI-2 to the rescue against antibiotic-induced intestinal dysbiosis?

Trends in Microbiology, 2015
The downside of antibiotic treatment of infectious diseases is a disturbed intestinal microbiota leading to reduced resistance against pathogen colonization. Work by Thompson et al. now suggests that antibiotic-induced intestinal dysbiosis can partially be counterbalanced by artificially increasing the levels of autoinducer-2 (AI-2), a well-known ...
Zhongke, Sun, Verena, Grimm, Christian U, Riedel   +2 more
openaire   +2 more sources

Biosensors for the Detection and Quantification of AI-2 Class Quorum-Sensing Compounds

2017
Intercellular small-molecular-weight signaling molecules modulate a variety of biological functions in bacteria. One of the more complex behaviors mediated by intercellular signaling molecules is the suite of activities regulated by quorum-sensing molecules. These molecules mediate a variety of population-dependent responses including the expression of
Sathish, Rajamani, Richard, Sayre
openaire   +2 more sources

Sùil air ais (2)

2015
openaire   +1 more source