Results 21 to 30 of about 159,079 (225)
Frontiers in Neuroscience, 2022 ObjectiveStroke patients often suffer from hand dysfunction or loss of tactile perception, which in turn interferes with hand rehabilitation. Tactile-enhanced multi-sensory feedback rehabilitation is an approach worth considering, but its effectiveness ...
Qiang Du +16 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Frontiers in Psychology, 2023 The new decade has been witnessing the wide acceptance of artificial intelligence (AI) in education, followed by serious concerns about its ethics. This study examined the essence and principles of AI ethics used in education, as well as the bibliometric
Liheng Yu, Zhonggen Yu
doaj +1 more source
SSRN Electronic JournalThis chapter examines AI’s transformative potential in education, focusing on Generative AI (GenAI) and Large Language Models (LLMs) while at the same time emphasizing the importance of grounding and guiding AI efforts with learning science and education research findings. It synthesizes analyses and expert recommendations, highlighting opportunities
Margherita Pagani +2 more
openaire +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Temporal Shift Module with Pretrained Representations for Speech Emotion Recognition
Intelligent ComputingRecent advances in self-supervised models have led to effective pretrained speech representations in downstream speech emotion recognition tasks. However, previous research has primarily focused on exploiting pretrained representations by simply adding a
Siyuan Shen +4 more
doaj +1 more source
Artificial intelligence applications in Latin American higher education: a systematic review
International Journal of Educational Technology in Higher Education, 2022 Over the last decade, there has been great research interest in the application of artificial intelligence (AI) in various fields, such as medicine, finance, and law.
Sdenka Zobeida Salas-Pilco, Yuqin Yang
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Grit and Second Language Learning Engagement: The Mediating Role of Affect Balance
Behavioral SciencesThe study of the relationship between key psychological attributes of learners and their engagement in second language (L2) learning helps to understand the critical personality mechanisms influencing language learning.
Chenggang Wu, Xiaoyong Tian, Hui Jin
doaj +1 more source