Results 131 to 140 of about 303,459 (294)

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

Advanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao, Dalin Chen, Ziyi Zhang, Jingxuan Ren, Chengcheng Zhao, Shengfang Wang, Mengyu Shang, Dawei Jiang, Yinuo Li, Su'an Tang, Kai Li, Xiaohui Zhang, Xiaogang Wang   +12 more
wiley   +1 more source

A Review on Catalytic Nanostructured Electrodes for Wearable and Implantable Abiotic Glucose Fuel Cells

Advanced Science, EarlyView.
This review identifies current and future directions in abiotic nanostructured catalysts to develop reliable and sustainable glucose fuel cells to power the next generation of bioelectronic devices. ABSTRACT The global rise in incidence of chronic diseases has led to the demand for innovative solutions that help patients manage their conditions with ...
Asghar Niyazi, Hannah S. Leese, Benjamin Metcalfe, Mirella Di Lorenzo   +3 more
wiley   +1 more source

Will Teacher-AI Collaboration Enhance Teaching Engagement?

Behavioral Sciences
Against the backdrop of the widespread integration of Artificial Intelligence (AI) into educational practices, collaboration between teachers and AI is profoundly influencing teaching behavior.
Lai-Jian Ding, Jia-Min Li, Bei-He Hui
doaj   +1 more source

Risk Information Seeking and Processing Model [PDF]

, 2015
Dunwoody, Sharon, Griffin, Robert J.
core   +2 more sources

Conversation Progress Guide : UI System for Enhancing Self-Efficacy in Conversational AI

Proceedings of the 2025 CHI Conference on Human Factors in Computing Systems
Accepted to ACM CHI2025'
Daeun Jeong, Sungbok Shin, Jongwook Jeong   +2 more
openaire   +3 more sources

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

Advanced Science, EarlyView.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin, Shulan Xiao, Krishna Jayant   +2 more
wiley   +1 more source

The influence of generative artificial intelligence on creative cognition of design students: a chain mediation model of self-efficacy and anxiety

Frontiers in Psychology
IntroductionThis study investigated the role of generative Artificial Intelligence (AI) in enhancing the creative cognition of design students, examining the mediating effects of self-efficacy and anxiety reduction.MethodsA quantitative approach was ...
Younjung Hwang, Yi Wu
doaj   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Artificial Intelligence Perceptions and Technostress in Staff Radiologists: The Mediating Role of Artificial Intelligence Acceptance and the Moderating Role of Self-Efficacy

Behavioral Sciences
This study examined how perceptions of artificial intelligence (AI) relate to technostress in healthcare professionals, testing whether AI acceptance mediates this relationship and whether self-efficacy moderates the formation of acceptance.
Giovanni Di Stefano, Sergio Salerno, Domenica Matranga, Manuela Lodico, Dario Monzani, Valeria Seidita, Roberto Cannella, Laura Maniscalco, Silvana Miceli   +8 more
doaj   +1 more source