Results 281 to 290 of about 2,464,013 (361)

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

AIDS in the Brazilian Amazon: epidemiological trends and disparities across states. [PDF]

open access: yesFront Public Health
Dos Anjos TAF   +12 more
europepmc   +1 more source

Lymphoma risk in autoimmune diseases with multiple medication use: analysis from the LIFE Study. [PDF]

open access: yesBlood Cancer J
Inokuchi A   +14 more
europepmc   +1 more source

Korean HIV/AIDS Cohort Study: Past Achievements, Present Directions, and Future Perspectives. [PDF]

open access: yesJugan Geongang Gwa Jilbyeong
Choi Y   +7 more
europepmc   +1 more source

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