Results 101 to 110 of about 9,392,423 (269)

La asignatura Ontogenia Humana y Sistema Osteomio-Articular: elementos importantes desde el punto de vista didáctico

open access: yesRevista Médica Electrónica
Durante los últimos años las transformaciones curriculares realizadas en la educación médica cubana han estado orientadas a elevar la calidad en la formación de los profesionales de la salud, por lo que la implementación de un nuevo plan de estudio D, ha
Marena Jordán Padrón   +2 more
doaj  

THE CONCEPTUAL MODEL OF THE EDUCATIONAL SUPPORT OF STUDENTS’ SOCIAL COMPETENCE FORMATION

open access: yesВестник Кемеровского государственного университета, 2013
The article deals with the conceptual model of the educational support of students’ social competence formation. The model is considered to be the theoretical and methodological foundation of the educational support provided by the academic staff.
E. N. Borisenko
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Adduct formed by chromium trioxide and zwitterionic quinolinic acid

open access: yesOpen Chemistry, 2010
Sundberg Markku   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Access to Data and Compute using Service Workbench: Repository of example code for AIM-AHEAD

open access: yes
<p>Initial release to register repository DOI on Zenodo</p ...
Simran Makwana
core   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

SUBJECTIVE ELEMENT OF BRIBE GIVING AND TAKING: CRIMINAL-LEGAL ANALYSIS

open access: yesRussian Journal of Economics and Law, 2012
The article views the main elements of subjective aspects of bribe giving and taking. Basing on materials law enforcement practice, the aims and motives of bribe giving and taking are described, as well as forms of guilt.
S. V. Izosimov
doaj  

Computational redesign of a hydrolase for nearly complete PET depolymerization at industrially relevant high-solids loading

open access: yesNature Communications
Biotechnological plastic recycling has emerged as a suitable option for addressing the pollution crisis. A major breakthrough in the biodegradation of poly(ethylene terephthalate) (PET) is achieved by using a LCC variant, which permits 90% conversion at ...
Yinglu Cui   +7 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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