Results 111 to 120 of about 7,461,211 (270)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Persisting Patronage: Challenges to Breaking Gender Barriers in Thai Elections
Journal of Current Southeast Asian AffairsThe 2023 elections witnessed the highest number of women in national parliament in Thailand's history. What explains this sharp rise in women's political leadership in Thailand?
Aim Sinpeng
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Piękny tulipan, trup i bez czystego cięcia. Bez-duszna estetyka Derridy
Teksty Drugie, 2016 This article explores a passage from Jacques Derrida’s book Truth in Painting, a discussion of the concept of beauty in Kant’s aesthetics. Dybel points out the original way in which Derrida reformulates this concept, attributing new meaning to its key ...
Paweł Dybel
doaj
Effetto del tipo di rivestimento PVD sulla resistenza alla corrosione
, 2012 La resistenza a corrosione di rivestimenti PVD in CrN è stata studiata con prove di polarizzazione elettrochimica condotte sia in NaCl siainHCl. E’ stata valuto l’effetto della tecnica di deposizione sulla qualità del rivestimento in termini di ...
POLA, Annalisa +4 more
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Studio della resistenza a corrosione in diversi ambienti di acciai per il settore automotive
, 2012 Uno dei requisiti più importanti delle lamiere di acciaio e delle parti automobilistiche esposte agli agenti atmosferici è la resistenza alla corrosione, che attualmente viene migliorata mediante zincatura. Per gli acciai innovativi di recente impiego,
CORNACCHIA, Giovanna +4 more
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source