Results 201 to 210 of about 7,461,211 (270)

An evaluation of the clinician-facing research dashboards from the Toronto Adolescent and Youth (TAY) Cohort Study in mental health care. [PDF]

PLOS Ment Health
Kuburi S, Foussias G, Davies J, Segovia AN, Wong J, Ameis S, Kozloff N, Quilty LC, Dickie E, Felsky D, Goldstein BI, Hawke LD, Polillo A, Nikolova YS, Wang W, TAY Cohort Study Team, Voineskos A, Cleverley K.   +17 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Implementing the Lung Donor (LUNDON) acceptability score in U.S. donor management and transplant decision-making: A multi-aim, mixed-methods protocol. [PDF]

PLoS One
Rossetti NE, Morrison S, Chang SH, Yan Y, Jaensch-Frie G, Liu CR, Seyoum NY, Katta M, Kumar A, Yang Z, Oncken C, Hamilton C, Schroy N, Stumbaugh K, Marklin G, Heiden B, Cummiskey B, Peskoe S, Hartwig M, Puri V, Baumann AA.   +20 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Antiretroviral therapy interferes with pseudovirus neutralization assays while Gag-specific T-cells influence mRNA vaccine outcomes in HIV patients. [PDF]

Sci Rep
Litwin SM, Trinh IV, Bai S, Sabino-Santos G, Tong S, Murrell AE, Scott JC, Chandra S, Elliott DH, Smira AR, Meyers EL, Srinivasan S, Francis M, Goff KA, Scheuermann SE, Zwezdaryk KJ, Maness NJ, Karger AB, Schieffelin JS, Gunn BM, Robinson JE, Zheng CY, Norton EB.   +22 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Observational Study on the Management of Children with Systemic Diseases During Dental Treatment. [PDF]

Children (Basel)
Akitomo T, Kusaka S, Nomura R.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Wearable Camera-Based Dietary Assessment of Mother-Father Dyads in Urban and Rural Households in Ghana. [PDF]

Curr Dev Nutr
Domfe CA, McCrory MA, Baranowski T, Sazonov E, Ghosh T, Raju V, Frost G, Steiner-Asiedu M, Sun M, Jia W, Lo B, Anderson AK.   +11 more
europepmc   +1 more source