Results 61 to 70 of about 7,461,211 (270)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of elite athletes’ aim orientation on basic psychological needs and fear of failure

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2019
Purpose: This research was carried out in order to analyze elite athletes’ aim orientation, basic psychological needs and fear of failure in perspective of several variables, and to reveal the differences among these variables.
R. Şeker
doaj   +1 more source

INFLUENZA DEI LUNGHI TEMPI DI SOLIDIFICAZIONE SULLE PROPRIETÀ MECCANICHE E MICROSTRUTTURALI DI GHISE SFEROIDALI RAFFORZATE PER SOLUZIONE SOLIDA

, 2016
Negli ultimi anni, le ghise sferoidali ferritiche rafforzate per soluzione solida tramite l’aumento del tenore di silicio (SSF-DI), grazie alle loro interessanti proprietà meccaniche, hanno riscontrato un grande interesse da parte del mondo accademico ...
FERRO, PAOLO, BONOLLO, FRANCO, BERTO, FILIPPO, BORSATO, THOMAS   +3 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Aim of Nature, Aims of Freedom

Croatian Journal of Philosophy
In these comments, I focus on Chapter 9 of Lara Ostaric’s The Critique of Judgment and the Unity of Kant’s Critical System, titled “Kant’s Teleological Philosophy of History.” My aim is to share some questions and critical remarks concerning the role that Ostaric assigns to nature’s alleged aim in human history, and suggest that moral development ...
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

МЕТОДИЧЕСКИЕ ОСНОВЫ ДИАГНОСТИРОВАНИЯ ИННОВАЦИОННЫХ ВОЗМОЖНОСТЕЙ ТУРИСТСКИХ ОРГАНИЗАЦИЙ

Sovremennye Issledovaniâ Socialʹnyh Problem, 2014
В статье сгруппированы основные проблемы, влияющие на инновационные процессы  в туристской организации. Туристская деятельность настолько разнообразна, что в ряде случаев ограничение круга изучения не ведет к формулированию представительных выводов ...
Oleg Vasilevich Chabanuk
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source