Results 71 to 80 of about 7,461,211 (270)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Le transmédia comme remédiation de la théorie du récit
Terminal, 2013 Olivier Aïm croise ici une réflexion sur le transmédia storytelling avec une réflexion sur la théorie des idées. Sa démarche s'inscrit dans une étude épistémologique de l'évolution des médias et des métiers médiatiques qui en découlent.
Olivier Aïm
doaj +1 more source
Journal of the American Medical Association, 1911 William Paul Crillon Barton was graduated from Princeton College in the class of 1805. It was the custom at that time for each member of the class to assume the name of some celebrated personage; young Barton adopted that of Count Paul Crillon, and the initials "P. C." were retained by him through life. He took his degree in medicine at the University
openaire +1 more source
Does belief aim (only) at the truth?
, 2012 It is common to hear talk of the aim of belief and to find philosophers appealing to that aim for numerous explanatory purposes. What belief’s aim explains depends, of course, on what that aim is.
Whiting, Daniel
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
THE CONCEPTUAL MODEL OF THE EDUCATIONAL SUPPORT OF STUDENTS’ SOCIAL COMPETENCE FORMATION
Вестник Кемеровского государственного университета, 2013 The article deals with the conceptual model of the educational support of students’ social competence formation. The model is considered to be the theoretical and methodological foundation of the educational support provided by the academic staff.
E. N. Borisenko
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Nature CommunicationsBiotechnological plastic recycling has emerged as a suitable option for addressing the pollution crisis. A major breakthrough in the biodegradation of poly(ethylene terephthalate) (PET) is achieved by using a LCC variant, which permits 90% conversion at ...
Yinglu Cui +7 more
doaj +1 more source