Results 71 to 80 of about 9,392,423 (269)
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
MODERNIZATION OF RUSSIA: TWO DEVELOPMENT PARADIGMS
The task of accelerated modernization of Russia may be solved provided objective causes of the system crisis spread all over the country as a certain mankind system are revealed and efficient crisis way-out instruments are found.
V. M. Bondarenko
doaj
USE OF VITAL STAINING IN STORED HUMAN PLATELETS MORPHOFUNCTIONAL ANALYSIS
Apheresis and pooled platelet concentrates, stored at 22°C during 5 days, were studied with morho-functional platelet rate analysis, based on vital cell staining and registration with fluorescent microscope.
M. S. Makarov +4 more
doaj +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Truth: the aim and norm of belief [PDF]
Invited contribution to The Aim of Belief, a special issue of Teorema, guest-edited by J ...
Whiting, Daniel
core +1 more source
FRAUDSTER'S PERSONALITY MOTIVATION SPHERE
The article reveals the peculiar motivations of an individual's unlawful behaviour, when committing a fraud for property acquisition of for obtaining rights for someone else's property.
R. Akhmetgareyev
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Does belief aim (only) at the truth?
It is common to hear talk of the aim of belief and to find philosophers appealing to that aim for numerous explanatory purposes. What belief’s aim explains depends, of course, on what that aim is.
Whiting, Daniel
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Le transmédia comme remédiation de la théorie du récit
Olivier Aïm croise ici une réflexion sur le transmédia storytelling avec une réflexion sur la théorie des idées. Sa démarche s'inscrit dans une étude épistémologique de l'évolution des médias et des métiers médiatiques qui en découlent.
Olivier Aïm
doaj +1 more source

