Results 91 to 100 of about 3,902,056 (289)

China’s Low-Carbon Scenario Analysis of CO2 Mitigation Measures towards 2050 Using a Hybrid AIM/CGE Model

open access: yesEnergies, 2015
China’s emissions continue to rise rapidly in line with its mounting energy consumption, which puts considerable pressure on China to meet its emission reduction commitments.
Wei Li, Hao Li, Shuang Sun
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Designing Attraction of Intervention Matrix (AIM) (Case study of interventionist actors in Syria) [PDF]

open access: yesآینده‌پژوهی دفاعی, 2018
Actor analysis is one of the most important methods in futures studies, actor analysis has a special status independently and with combination to other methods especially with scenario planning methods.
Mohammad Amin Ghalambor   +3 more
doaj  

Project AIM

open access: yes, 2023
This is the repository for materials associated with Project AIM (Autism Intervention Meta-analysis), a meta-analysis of studies of interventions for young autistic ...
Jacob I. Feldman, Micheal Sandbank
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Preferences for Mobile Apps That Aim to Modify Alcohol Use: Thematic Content Analysis of User Reviews

open access: yesJMIR mHealth and uHealth
BackgroundNearly one-third of adults in the United States will meet criteria for alcohol use disorder in their lifetime, yet fewer than 10% of individuals who meet for alcohol use disorder criteria will receive treatment for it.
Megan Kirouac, Christina Gillezeau
doaj   +1 more source

Scaling-up the Systems Analysis and Improvement Approach for prevention of mother-to-child HIV transmission in Mozambique (SAIA-SCALE): a stepped-wedge cluster randomized trial

open access: yesImplementation Science, 2019
Background The introduction of option B+—rapid initiation of lifelong antiretroviral therapy regardless of disease status for HIV-infected pregnant and breastfeeding women—can dramatically reduce HIV transmission during pregnancy, birth, and ...
Kenneth Sherr   +14 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Strengthening the evidence-base of integrated care for people with multi-morbidity in Europe using Multi-Criteria Decision Analysis (MCDA)

open access: yesBMC Health Services Research, 2018
Background Evaluation of integrated care programmes for individuals with multi-morbidity requires a broader evaluation framework and a broader definition of added value than is common in cost-utility analysis.
Maureen Rutten-van Mölken   +17 more
doaj   +1 more source

Harmonic analysis and mitigation in distribution grids with high penetration of power inverters [PDF]

open access: yes, 2019
Inverters of large heat pumps in an urban low voltage grid generate current harmonics and cause consequently significant variations of the respective voltage harmonics.
Rupp, Adrian   +5 more
core   +1 more source

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