Results 81 to 90 of about 36,235,438 (278)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Analysis of Performance Characteristics and Development Overview of US Navy AIM-174B Very Long-Range Air-to-Air Missile [PDF]
AIM-174B is a new very long-range air-to-air missile developed by the US Navy based on the RIM-174 "Standard-6" surface-to-air missile, it is also the air-to-air missile with the longest range ever equipped by US Air Force/Navy combat aircraft.On the ...
Chen Li, Tian Hao, Yuan Cheng, Zheng Ke
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
EU Presidency Programmes as a Genre
Along with acting in political, economic and social arenas of the European Union, Latvia was also honoured to preside over the Council of Europe in 2015.
Jana Kuzmina
doaj
Analysis of the traditional arts and craft industry with the aim to improve the sustainable development of tourism in Montenegro [PDF]
Tourism sector in Montenegro, despite an abundance of crafts, has not recognized the importance of their valorisation. Therefore, the purpose of this paper is to examine potential problems and weaknesses of craft sector, to explore artisans ' willingness
Janković Đorđina +1 more
doaj +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
The thioether-functionalized 2-azabutadiene (iPrS)2C=C(H)-N=CPh2 L1 ligates to Mn(CO)5Br to form the five-membered chelate compound fac-MnBr(CO)3[(iPrS)2C=C(H)-N=CPh2] MnPropBr, whose crystal structure has been determined from X-ray diffraction data.
Marek M. Kubicki +2 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

