Results 41 to 50 of about 325,139 (297)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

An experimental study on the filtration performance of a poly-alpha-olefin-compatible expanded polytetrafluoroethylene high-efficiency particulate air filter

open access: yesSouth African Journal of Chemical Engineering, 2022
Filter media made of expanded polytetrafluoroethylene filters are known to be incompatible with poly-alpha-olefin or any oil-based challenge particles, and thus, filters made of expanded polytetrafluoroethylene had limited use in pharmaceutical ...
Tee Lin   +5 more
doaj   +1 more source

Investigation of an R134A Refrigerant/Iso 32 Polyol Ester Oil Mixture in Condensation [PDF]

open access: yes, 2001
Air Conditioning and Refrigeration Project ...
Chato, J.C.   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Discussion of the Energy-Saving Benefits of Heat Insulating Coating for Building Windows

open access: yesMATEC Web of Conferences, 2016
Nano transparent heat insulating coating is applied to window glass in this study. The heat insulating coating absorbs thermal radiation, and reduces the thermal radiation transmittance of glass, thus, preventing the building heat load from increasing in
Chang Jing-Yi   +7 more
doaj   +1 more source

Buildings for low energy air conditioning [PDF]

open access: yes, 1998
Over half of global warming is thought to be attributable to the burning of fossil fuelsand slightly less than half of this is due to conditioning the environment withinbuildings.
Oreszczyn, T
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The effects of surface modification on aerodynamic characteristics of airfoil DU 06 W 200 at low Reynolds numbers,

open access: yesInternational Journal of Thermofluids, 2022
In this paper the flow characteristics and velocity fields over the vertical axis wind turbines DU 06 W 200 airfoil developed by Delft University of Technology and some other innovative designs are examined by computational fluid dynamics (CFD ...
Omid Ali Zargar   +6 more
doaj   +1 more source

UK domestic air conditioning: a study of occupant use and energy efficiency [PDF]

open access: yes, 2008
This paper presents the results of a study of air-conditioning usage in homes in the southeast of England. First part of the study consisted surveying 13 dwellings with air-conditioning for a series of 4 week periods during the summer of 2004.
Oreszczyn, T., Pathan, A., Young, A.
core  

Building thermal performance, extreme heat, and climate change [PDF]

open access: yes, 2017
The leading source of weather-related deaths in the United States is heat, and future projections show that the frequency, duration, and intensity of heat events will increase in the Southwest.
Chester, MV   +5 more
core   +2 more sources

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