Results 41 to 50 of about 284,823 (311)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Investigation on the performance of air source heat pump system with new environment friendly refrigerants for a low carbon building [PDF]

, 2016
Energy is an important development factor. It is consumed in different format from different sources in daily human activities. Solar energy, as the most fundamental renewable energy resource, serves in a clean, domestic and environmentally friendly way
Cuce, E, Ding, Y, Lu, C, Riffat, S
core  

Dynamic thermal simulation of horizontal ground heat exchangers for renewable heating and ventilation of buildings [PDF]

, 2016
A ground heat exchanger is used to transfer thermal energy stored in soil in order to provide renewable heating, cooling and ventilation of a building.
Bansal, Bottarelli, Chong, Cosby, Darkwa, Gan, Gan, Gan, Gan, Gnielinski, Gonzalez, Guohui Gan, Maerefat, Mei, Mihalakakou, Niu, Ozgener, Philip, Santamouris, Svec, Tiwari, Wu   +21 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Experimental Study on the Combined Heat Storage and Supply of Air/Water-Source Heat Pumps

Buildings
As the application of renewable energy becomes increasingly extensive, heat pump technology with renewable energy as the heat source is achieving good results. Air-source heat pumps and water-source heat pumps can be widely used in cold areas.
Qi Zhao, Shijie Gu, Shuang Ma, Bo Tian, Bowen Chu, Hongwen Jin   +5 more
doaj   +1 more source

Hourly Calculation Method of Air Source Heat Pump Behavior [PDF]

Buildings, 2016
The paper describes an hourly simplified model for the evaluation of the energy performance of heat pumps in cooling mode maintaining a high accuracy and low computational cost. This approach differs from the methods used for the assessment of the overall energy consumption of the building, normally placed in the so-called white or black box models ...
Ludovico Danza, Lorenzo Belussi, Italo Meroni, Michele Mililli, Francesco Salamone   +4 more
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Carbon-ammonia pairs for adsorption refrigeration applications : ice making, air conditioning and heat pumping [PDF]

, 2009
A thermodynamic cycle model is used to select an optimum adsorbent-refrigerant pair in respect of a chosen figure of merit that could be the cooling production (MJ m(-3)), the heating production (MJ m(-3)) or the coefficient of performance (COP).
Critoph, Robert E., Metcalf, Steven J., Tamainot-Telto, Zacharie, Thorpe, Roger, Zhong, Y.   +4 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source