Results 41 to 50 of about 286,138 (309)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Heating performance of an air source heat pump with a portable thermoelectric subcooler

Case Studies in Thermal Engineering
This study investigates the heating performance of an integrated air-source heat pump (ASHP) with a thermoelectric subcooler (TES) module, revealing significant performance enhancements, particularly in colder temperatures. Results show that adding the portable TES boosts the ASHP's heating capacity, making it feasible for residential applications. The
Yifeng Hu, Bo Shen, Sreenidhi Krishnamoorthy, Don Shirey   +3 more
openaire   +2 more sources

Impact of residential energy system sizing and control over heat pump’s system cost and reliability [PDF]

, 2011
Using a simulation-based approach, this work analyses the impact that different energy unit sizes and control methodologies will have over the capital and running costs of an air source heat pump (ASHP) system to be installed in a refurbished dwelling. A
Cooper, Catherine, Duncan, Douglas, Kelly, Nicolas, Lira, Lucas   +3 more
core  

Modelling and simulation of a heat pump for simultaneous heating and cooling [PDF]

, 2012
International audienceThe heat pump for simultaneous heating and cooling (HPS) carries out space heating, space cooling and hot water production for small office and residential buildings. It works under heating, cooling and simultaneous modes to produce
Byrne, Paul, Lénat, Yves, Miriel, Jacques   +2 more
core   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Experimental Study on the Combined Heat Storage and Supply of Air/Water-Source Heat Pumps

Buildings
As the application of renewable energy becomes increasingly extensive, heat pump technology with renewable energy as the heat source is achieving good results. Air-source heat pumps and water-source heat pumps can be widely used in cold areas.
Qi Zhao, Shijie Gu, Shuang Ma, Bo Tian, Bowen Chu, Hongwen Jin   +5 more
doaj   +1 more source

Performance analysis of air source heat pumps using detailed simulations and comparison to field trial data [PDF]

, 2010
The take-up of heat pump technologies in the UK domestic sector has lagged far behind other countries in Europe and North America due primarily to the ready availability of cheap natural gas; this has led to the predominance of gas central heating ...
Cockroft, J., Ghauri, S., Kelly, N.J.
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Carbon-ammonia pairs for adsorption refrigeration applications : ice making, air conditioning and heat pumping [PDF]

, 2009
A thermodynamic cycle model is used to select an optimum adsorbent-refrigerant pair in respect of a chosen figure of merit that could be the cooling production (MJ m(-3)), the heating production (MJ m(-3)) or the coefficient of performance (COP).
Critoph, Robert E., Metcalf, Steven J., Tamainot-Telto, Zacharie, Thorpe, Roger, Zhong, Y.   +4 more
core   +1 more source

Thermoreflectance Detection of Point Defects Resulting from Focused Ion Beam Milling

Advanced Engineering Materials, EarlyView.
Focused ion beam (FIB) milling is a common tool for nanoscale material processing, however irradiation damage, redeposition, and contamination can occur. We use several characterization tools to show FIB‐induced effects beyond 1 mm from the milled area.
Thomas W. Pfeifer, Eric R. Hoglund, Anton V. Ievlev, Patrick E. Hopkins   +3 more
wiley   +1 more source