Results 191 to 200 of about 172,231 (266)

Petermann Glacier on the brink: Progress, challenges and insights. [PDF]

Sci Adv
Fahrner D, Colgan WT, MacGregor JA, Washam P, Løkkegaard A, Khan SA.   +5 more
europepmc   +1 more source

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

Climatic reach of small-scale turbulence in the ocean interior. [PDF]

Nat Commun
Cimoli L, Mashayek A, Naveira Garabato AC, Caulfield CP, Alford MH, Baker L, Cael BB, Fernández Castro B, de Lavergne C, Ellison E, Gebbie G, Gula J, Heimbach P, Lanham J, Le Boyer A, Oglethorpe K, Peltier WR, Pillar HR, Piotrowski AM, Purkey SG, Reynard N, Shuckburgh E, Siegert MJ, Silvano A, Skinner LC, Spingys CP, Talley LD, Taylor JR, Voet G, Williams RG, Wilson C, Wynne-Cattanach BL.   +31 more
europepmc   +1 more source

Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy

Advanced Science, EarlyView.
A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu, Jing‐Chu Hu, Ye‐Fan Hu, Wen‐Jun Li, Li Rong, Ren‐Hao Li, Yuan Yao, Lehan Hu, Xiao‐Lei Wang, Bao‐Zhong Zhang, Yicheng Lu, Shing‐Fung Chow, Canhui Su, Thomas Yau, Clive Yik‐Sham Chung, Jian‐Dong Huang   +15 more
wiley   +1 more source

Weaker and more frequent Mediterranean sea breezes in a warming climate. [PDF]

Sci Rep
Bedoya-Valestt S, Azorin-Molina C, Plaza-Martin NP, Minola L, Gimeno L, Andres-Martin M, Vicente-Serrano SM, Chen D.   +7 more
europepmc   +1 more source

Adjustment of Air Conditioning and Air Circulation to prevent yarn Breakage

Journal of the Textile Machinary Society, 1960
openaire   +2 more sources

Static Drainage H2/O2 PEM Fuel Cells Enabled by Water Transport Plates: Pore‐Scale Design and Transport Mechanisms

Advanced Science, EarlyView.
The WTP is a key component of static drainage PEMFCs, enabling cathode water removal and gas sealing through capillary forces. This work investigates the mechanisms governing WTP drainage and sealing performance and develops predictive approaches for WTP design optimization.
Mengdi Guo, Diankai Qiu, Dong Zhu, Linfa Peng   +3 more
wiley   +1 more source

Repeated ethanol exposure in female rats impairs cerebral endothelial function and increases cerebrovascular stiffness. [PDF]

Eur J Pharmacol
Baumoel EJ, Heitkamp MC, Thaqi A, Luchetta J, DeMarco GM, Karkhanis AN, Chapman AC.   +6 more
europepmc   +1 more source

TNAP and PHOSPHO1 Function Synergistically to Afford Critical Control Over the Mineralization of the Postnatal Murine Skeleton

Advanced Science, EarlyView.
Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne, Aikta Sharma, Scott Dillon, Jacob Keen, Soher N. Jayash, Natalie Crump, Lucinda A.E. Evans, Maya Karmali, Worachet Promruk, Claire E. Clarkin, Sonoko Narisawa, Louise Stephen, Brian L. Foster, José Luis Millán, Colin Farquharson, Katherine A. Staines   +15 more
wiley   +1 more source