Results 51 to 60 of about 3,128,676 (311)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
R32 Compressor for Air conditioning and Refrigeration applications in China [PDF]
, 2012 This paper evaluates the compressor performance and reliability impact by using R32 refrigerant for air conditioning (residential and commercial system); Performance and reliability impacts are compared with different popular refrigerants used in China ...
Zhan, Honghong +3 more
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Analysis of Free Vibration Features in FGM Plates
مجلة النهرين للعلوم الهندسيةFunctionally graded materials (FGM) are a category of composite materials distinguished by specific design attributes that allow them to serve various purposes and applications.
Sanaa Samir +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
New Energy-Efficient Electromagnetic Clutch for Automotive Air Conditioning Compressors [PDF]
, 2012 Even if the air conditioning is switched off, the internal combustion engine in today’s cars continues to drive the common compressor. To avoid resulting power losses, the automotive industry aspires to apply electromagnetic clutches.
Aurich, Joerg +3 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Air Conditioning Hybrid Electric Vehicles while Stopped in Traffic [PDF]
, 2004 HEVs idle their engine during the stops to meet the cooling and heating needs. But, idling decreases fuel economy and increases engine wear and emissions.
T. Malik +3 more
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Dynamic Modeling and Advanced Control of Air Conditioning and Refrigeration Systems [PDF]
, 2006 Over 15 billion dollars is spent on energy for residential air-conditioning alone each year, and air conditioning remains the largest source of peak electrical demand.
Rasmussen, Bryan P., Alleyne, Andrew G.
core