Results 61 to 70 of about 3,128,676 (311)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Development of a Transient System Model of Mobile Air-Conditioning Systems [PDF]

open access: yes, 1998
A transient model was developed to predict the behavior of the vapor compression cycle of a mobile air-conditioning system. Mobile air-conditioning systems operate in a transient mode due to variations in compressor speed, variations in condenser air ...
Hemami, T.L.
core  

Air Conditioning Systems : Design and Energy efficiency [PDF]

open access: yes, 2012
Air conditioning systems have become an integral part of many modern buildings. Proper design and operation of air conditioning systems have significant impact not only on the energy use and greenhouse gas emissions from the buildings, but also on the ...
Guan, Lisa, Chen, Guangnan
core   +2 more sources

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Modeling of an Automotive Air Conditioning Compressor Based on Experimental Data [PDF]

open access: yes, 1992
The objective of the current study was to develop a model for the steady-state performance of a reciprocating automotive air conditioning compressor. The model equations were composed of analytical equations based on simple energy and mass balances in ...
Darr, J.H.
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Development and Validation of a Room Air Conditioning Simulation Model [PDF]

open access: yes, 1997
"Component submodels for a room air conditioner computer simulation were developed and validated using data from a 1.5-ton room air conditioner. The room air conditioner was tested over an extremely wide range: both indoor and outdoor temperatures varied
Porter, K.J.   +4 more
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Semi-Theoretical Steady State and Transient Modeling of a Mobile Air Conditioning Condenser [PDF]

open access: yes, 1993
The objective of the work presented in this paper is the development of a transient model of a mobile air conditioning condenser. Refmement of a steady state model is an intermediate task that is especially important for the steady state forcing function
VanderZee, J.C.
core  

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