Results 51 to 60 of about 10,065,141 (353)
Design procedure for a wind-wheel with self-adjusting blade mechanism
Trudy Odesskogo Politehničeskogo Universiteta, 2014 Developed is a wind-wheel design equipped with the self-adjusting blade. The blade is positioned eccentrically to the balance wheel and can freely rotate around its axis. Elaborated is the method of calculating the energy characteristics for a wind-wheel
Gennady A. Oborsky +2 more
doaj +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
A Prosthetic Socket with Active Volume Compensation for Amputated Lower Limb
Sensors, 2021 Typically, the actual volume of the residual limb changes over time. This causes the prosthesis to not fit, and then pain and skin disease. In this study, a prosthetic socket was developed to compensate for the volume change of the residual limb.
Ji-Hyeon Seo +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Journal of Hydraulic ResearchThe authors thank the three reviewers for their constructive feedback.
Daniel Valero +6 more
openaire +3 more sources
Applied SciencesThis study evaluates and estimates the agronomic effectiveness of food waste-derived fertilizers by analyzing plant yield and the internal efficiency of nitrogen utilization (IENU) via statistical and machine learning models.
Ksawery Kuligowski +7 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Rekayasa SipilOne way to increase runway capacity is to set the Runway Occupancy Time Take-Off (ROTT) standard. Following the Aeronautical Information Publication of Soekarno-Hatta International Airport, the ROTT standard is set at 90 seconds.
Mohammad Ardiansyah Putra Indrawan +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source