Results 71 to 80 of about 5,737,218 (322)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A comparison of statistical and machine learning methods for creating national daily maps of ambient PM$_{2.5}$ concentration [PDF]

open access: yes, 2019
A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants ...
Berrocal, Veronica J.   +6 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Evaluation of superficial tumor treatment using radixact with the kilovoltage computed tomography system: dosimetric and clinical feasibility of super stuff bolus

open access: yesFrontiers in Oncology
BackgroundFlat commercial boluses for superficial tumor radiation therapy often fail to conform to irregular body surfaces, resulting in air gaps that reduce dose coverage and uniformity.
Ryuichi Yada   +4 more
doaj   +1 more source

A nonlinearity in permanent-magnet systems used in watt balances

open access: yes, 2014
Watt balances are used to measure the Planck constant and will be used in the future to realize mass at the kilogram level. They increasingly rely on permanent magnet systems to generate the magnetic flux.
Li, Shisong   +2 more
core   +1 more source

Effect of Air Gap Entrapped in Firefighter Protective Clothing on Thermal Resistance and Evaporative Resistance

open access: yes, 2018
Heat and water vapor transfer behavior of thermal protective clothing is greatly influenced by the air gap entrapped in multilayer fabric system. In this study, a sweating hot plate method was used to investigate the effect of air gap position and size ...
Hualing He, Zhicai Yu
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Identification of slot discharges in rotating machine insulation system using variable frequency PD measurement

open access: yesHigh Voltage, 2018
Slot discharge studies are very important from the insulation diagnosis perspective. Further in practice, testing of rotating machines with power frequency requires sources which are quite bulky and costly.
Ramesh P. Nair   +3 more
doaj   +1 more source

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