Results 101 to 110 of about 136,713 (288)

Micro/nanorobots for detecting and eliminating biological and chemical warfare agents

BMEMat, EarlyView.
Fuel‐powered and field‐driven micro/nanorobots provide a cutting‐edge platform to safeguard national security and defense. This review reports the latest research progress in micro/nanorobots in sensing and detoxifying biological and chemical warfare agents.
Song Li, Huaijuan Zhou, Di Shi, Zdeněk Sofer, Jinhua Li   +4 more
wiley   +1 more source

Synthetic modeling: A cell‐free approach for faster implementation of Raman spectroscopy in cell culture

Biotechnology Progress, EarlyView.
Abstract Monitoring cell culture is crucial for gaining a deeper understanding of processes and ensuring the production of safe and high‐quality products. The capability to measure in real time several parameters of interest can be achieved with Raman spectroscopy.
Célia Sanchez, Hadi El Radi, Nathan Gay, Johan Cailletaud, Kévin Grollier, Fabrice Thomas, Thierry Gonthiez   +6 more
wiley   +1 more source

Microbiological safety and antibiotic resistance risks at a sustainable farm under large-scale open-air composting and composting toilet systems [PDF]

, 2020
Ning Liu, Like Xu, Lujia Han, Guangqun Huang, Lena Ciric   +4 more
openalex   +1 more source

5‐Aza combined with VPA reprograms human T lineage acute leukemia Jurkat cells into B‐cell‐like cells by epigenetic activation of PAX5

Biotechnology Progress, EarlyView.
Abstract Epigenetic regulation plays an important role in cell fate reprogramming. Here, we found that inhibitors of epigenetic modifiers, including VPA, TSA, and 5‐Aza‐2'‐deoxycytidine, can induce phenotypic transformation from Jurkat cells into B‐cell‐like cells. When Jurkat cells were treated with 5‐Aza combined with VPA, B cell and stem cell marker
Wenjin Xi, Guoxu Zheng, Xu Chen, Baile Zuo, Wei Wang, Yufang Li, Chunmei Zhang, Jie Chu, Xiuli Mu, Weihong Wen, Tao Wang, An‐Gang Yang   +11 more
wiley   +1 more source

Comparison of Streptococcus pneumoniae isolates occurring in optochin-susceptible and optochin-resistant variants by analyzing whole-genome sequencing data

Microbiology Spectrum
The paper presents the study of a set of isolates of Streptococcus pneumoniae, which comprised two heterogeneous subpopulations, one of which was susceptible and the other resistant to optochin.
Sandra Vohrnová, Jana Kozáková, Michal Honskus   +2 more
doaj   +1 more source

N‐1 semi‐continuous transient perfusion in shake flask for ultra‐high density seeding of CHO cell cultures in benchtop bioreactors

Biotechnology Progress, EarlyView.
Abstract One strategy to enhance the production of biological therapeutics is using transient perfusion in the preculture (N‐1 stage) to seed the production culture (N stage) at ultra‐high cell densities (>10 x 106 viable cells/mL). This very high seeding density improves cell culture performance by shortening the timeline and/or achieving higher final
Lucas Lemire, Sebastian‐Juan Reyes, Yves Durocher, Robert Voyer, Olivier Henry, Phuong Lan Pham   +5 more
wiley   +1 more source

A novel multiparameter sensor for shake flask cultivations: Online biomass, dissolved oxygen, and fluorescence monitoring for comprehensive bioprocess characterization

Biotechnology Progress, EarlyView.
Abstract Shake flasks are one of the most widely used cultivation vessels in biotechnological process development. To improve the process understanding, new technologies have been reported for online monitoring of different parameters like oxygen, pH, or biomass in the last couple of years.
Lara Strehl, Anna‐Lena Kuhn, Kyra Hoffmann, Marcel Mann, Jørgen Barsett Magnus   +4 more
wiley   +1 more source

Editorial: Functional Metagenomics for Enzyme Discovery

Frontiers in Microbiology, 2022
Vanessa A. Varaljay, Trevor C. Charles, Rolf Daniel   +2 more
doaj   +1 more source

Minimizing batch‐to‐batch variability of a live virus vaccine by process analytical technologies

Biotechnology Progress, EarlyView.
Abstract For bioprocesses producing live virus, such as enterovirus Coxsackievirus A21, viral titer (infectivity basis) decay rates can exceed 30% within a day. Consequently, harvest timing is paramount. To optimize titer at harvest, a continuous viral product titer model was generated to elucidate kinetics.
Katherine Forrester, Thomas R. Blanda, Marena Trauger, Rachel Thompson, Neil Templeton   +4 more
wiley   +1 more source

Transcriptomic functional characterization of recombinant adeno‐associated virus producing cell line adapted to suspension‐growth

Biotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo, Prahalad Srinivasan, Yu‐Chieh Lin, Min Lu, Carissa Rungkittikhun, Qi Zhang, Wei‐Shou Hu   +6 more
wiley   +1 more source