Results 81 to 90 of about 383,906 (352)

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source

Fibroblast-like synoviocytes mediate the generation of soluble PD-1 in an MMP-9-dependent manner: a novel target therapy for rheumatoid arthritis

Frontiers in Immunology
IntroductionDysregulated T cell homeostasis leading to enhanced immune responses is a critical pathogenic mechanism in rheumatoid arthritis (RA). Programmed cell death protein 1 (PD-1) is a crucial immune checkpoint that modulates T cell activity ...
Chao Yang, Chao Yang, Miao Ma, Kangjie Yu, Yi Wang, Yuting Zhang, Yan Shen, Jun Wang, Xiaoke Wang, Xiaoke Wang, Lulu Luo, Lulu Luo, Ya Zhao   +12 more
doaj   +1 more source

Bioaugmentation for Improved Recovery of Anaerobic Digesters After Toxicant Exposure [PDF]

, 2010
Bioaugmentation was investigated as a method to decrease the recovery period of anaerobic digesters exposed to a transient toxic event. Two sets of laboratory-scale digesters (SRT = 10 days, OLR = 2 g COD/L-day), started with inoculum from a digester ...
Maki, James, Schauer-Gimenez, Anne, Struble, Craig, Zitomer, Daniel   +3 more
core   +1 more source

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, EarlyView.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source

The protective role of Mertk in JEV-induced encephalitis by maintaining the integrity of blood–brain barrier

Virology Journal
Japanese encephalitis is an acute infectious disease of the central nervous system caused by neurotropic Japanese encephalitis virus (JEV). As a member of TAM (Tyro3, Axl and Mertk) family, Mertk has involved in multiple biological processes by engaging ...
Chuanyu Luo, Mengyuan Li, Peiyu Bian, Jiali Yang, Xiamei Liao, Yangchao Dong, Chuantao Ye, Fanglin Zhang, Xin Lv, Qianqian Zhang, Yingfeng Lei   +10 more
doaj   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Mitochondrial CircRNA CircMT‐RNR2 Safeguards Antioxidant Defense to Support Fibroblast Functions in Wound Repair

Advanced Science, EarlyView.
CircMT‐RNR2 promotes wound healing by enhancing fibroblast proliferation, migration, contraction, and extracellular matrix (ECM) production. It sustains mitochondrial redox balance by stabilizing the antioxidant protein PRDX3, thereby reducing ROS‐induced damage. In diabetic foot ulcers, hypoxia, hyperglycemia, and reduced FGF2 and EGF expression lower
Guanglin Niu, Jennifer Geara, Yongjian Chen, Lihua Luo, Yanwei Xiao, Zhuang Liu, Margaux Gaborieau, Ling Pan, Edmund Loh, Dongqing Li, Pehr Sommar, Aoxue Wang, Xiaowei Zheng, Ning Xu Landén   +13 more
wiley   +1 more source

Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents

Nature Communications
Hantaan virus (HTNV) is asymptomatically carried by rodents, yet causes lethal hemorrhagic fever with renal syndrome in humans, the underlying mechanisms of which remain to be elucidated. Here, we show that differential macrophage responses may determine
Hongwei Ma, Yongheng Yang, Tiejian Nie, Rong Yan, Yue Si, Jing Wei, Mengyun Li, He Liu, Wei Ye, Hui Zhang, Linfeng Cheng, Liang Zhang, Xin Lv, Limin Luo, Zhikai Xu, Xijing Zhang, Yingfeng Lei, Fanglin Zhang   +17 more
doaj   +1 more source

New Scientific and Technological Developments of Relevance to the Fifth Review Conference [PDF]

, 2001
Ye
Pearson, Graham S.
core  

Influence of bioturbation by the polychaete Nereis diversicolor on the structure of bacterial communities in oil contaminated coastal sediments [PDF]

, 2007
Patterns of change in the structure of bacterial communities monitored by ribosomal intergenic spacer analysis (RISA) in oil contaminated sediments inhabited or not by the marine polychaete Nereis diversicolor were studied during 45 days under laboratory
Acquaviva, Monique, Cornet-Barthaux, Véronique, Cuny, Philippe, Gilbert, Franck, Grossi, Vincent, Miralles, Gilles, Stora, Georges   +6 more
core   +5 more sources