Results 141 to 150 of about 385,213 (333)

Artificial intelligence and machine learning‐assisted digital applications for biopharmaceutical manufacturing

Biotechnology Progress, EarlyView.
Abstract Artificial intelligence and automation are no longer just buzzwords in the biopharmaceutical industry. The manufacturing of a class of biologics, comprising monoclonal antibodies, cell therapies, and gene therapies, is far more complex than that of traditional small molecule drugs.
Shyam Panjwani, Hao Wei, John Mason
wiley   +1 more source

Multi-omic characteristics of longitudinal immune profiling after breakthrough infections caused by Omicron BA.5 sublineagesResearch in context

EBioMedicine
Summary: Background: Omicron sub-variants breakthrough infections (BTIs) have led to millions of coronavirus disease 2019 (COVID-19) cases worldwide. The acute-phase immune status is critical for prognosis, however, the dynamic immune profiling of COVID-
Yanhua Li, Shijie Qin, Lei Dong, Yunfeng Xiao, Yanan Zhang, Yali Hou, Shitong Qiao, Rong Zhang, Ying Li, Yanmin Bao, Xin Zhao, Yueyun Ma, George Fu Gao   +12 more
doaj   +1 more source

Effect of cell retention techniques in Komagataella phaffii lab‐scale continuous processes

Biotechnology Progress, EarlyView.
Abstract Perfusion technologies play a growing role in the implementation of continuous processes for biotherapeutics production in mammalian‐based manufacturing. However, their application to alternative production hosts is limited. Cell retention systems are of key importance for the efficiency of perfusion bioreactors.
Marina Y. Linova, Satish K. Kodiripaka, Edite Martins, Sobhana A. Sripada, Stefano Menegatti, John M. Woodley   +5 more
wiley   +1 more source

Analysis of the economic viability and environmental impacts of a conceptual process model for the recovery of lactic acid from spent media in cultivated meat production

Biotechnology Progress, EarlyView.
Abstract Scaled production of cultivated meat (CM) will co‐produce large volumes of spent media. Recycling of abundant metabolites such as lactic acid in spent media offers an opportunity for valorization and reduction of the carbon footprint of CM production; however, the feasibility has yet to be examined.
Josh Wimble, Reina Ashizawa, Elliot W. Swartz   +2 more
wiley   +1 more source

Editorial: Functional Metagenomics for Enzyme Discovery

Frontiers in Microbiology, 2022
Vanessa A. Varaljay, Trevor C. Charles, Rolf Daniel   +2 more
doaj   +1 more source

Comparison of Streptococcus pneumoniae isolates occurring in optochin-susceptible and optochin-resistant variants by analyzing whole-genome sequencing data

Microbiology Spectrum
The paper presents the study of a set of isolates of Streptococcus pneumoniae, which comprised two heterogeneous subpopulations, one of which was susceptible and the other resistant to optochin.
Sandra Vohrnová, Jana Kozáková, Michal Honskus   +2 more
doaj   +1 more source

Microbiological and total particles suspended indoor air quality at the Universidad Iberoamericana Torreón

, 2020
José Antonio Martínez-Villalba, Mayra Luna-Porres, Alejandra Mayela Gilio-Villa, Sebastián Jafet Arredondo-Guerrero   +3 more
openalex   +1 more source

Spatiotemporal establishment of dense bacterial colonies growing on hard agar. [PDF]

, 2019
The physical interactions of growing bacterial cells with each other and with their surroundings significantly affect the structure and dynamics of biofilms.
Cremer, Jonas, Hwa, Terence, Li, Bo, Sun, Hui, Warren, Mya R, Yan, Yue   +5 more
core  

A case study showing the role of hydrophobicity variants and other enriched mAb proteoforms on filterability through a virus filter with productivity improvement measures

Biotechnology Progress, EarlyView.
Abstract A rapid assessment of manufacturability for drug candidates is crucial for advancing a prospective biotherapeutic from a candidate to a bulk drug substance. A lot‐to‐lot approach to manufacturability is adopted where each biologic batch is assessed for manufacturability as a bulk, unfractionated pool.
Solomon Isu, Derek Silva, Melissa Holstein, Angela Lewandowski, Kristina Cunningham, Adam Sokolnicki, Bala Raghunath   +6 more
wiley   +1 more source

Microbiological air quality in tie-stall dairy barns and some factors that influence it

, 2011
Silvana Popescu
openalex   +1 more source