Results 131 to 140 of about 3,546,504 (308)

Demonstration of nanofiltration‐based virus safety for AAV manufacturing using model viruses

Biotechnology Progress, EarlyView.
Abstract Virus safety for biopharmaceutical products has been a well‐established concern for several decades. While various virus reduction steps have been identified and implemented for traditional plasma‐derived and monoclonal antibody products, there are various challenges to achieving the same virus safety in emerging gene therapy products.
Brian Buesing, Tomoki Igi, Daniel Strauss   +2 more
wiley   +1 more source

Comparison of Streptococcus pneumoniae isolates occurring in optochin-susceptible and optochin-resistant variants by analyzing whole-genome sequencing data

Microbiology Spectrum
The paper presents the study of a set of isolates of Streptococcus pneumoniae, which comprised two heterogeneous subpopulations, one of which was susceptible and the other resistant to optochin.
Sandra Vohrnová, Jana Kozáková, Michal Honskus   +2 more
doaj   +1 more source

Ninth Flyer 17_3_2007

, 2014
The quarterly newsletter, The Ninth Flyer, published by the Ninth Air Force Association, Inc.
9th Air Force Association
core  

High‐throughput development and scale‐up of recombinant adeno‐associated virus 5 anion‐exchange chromatography for high‐purity capsid separation

Biotechnology Progress, EarlyView.
High‐throughput anion‐exchange chromatography process development enables scalable purification of high‐purity recombinant adeno‐associated virus capsids. Abstract Recombinant adeno‐associated virus (rAAV) production commonly yields a high proportion of empty and partially filled capsids, necessitating downstream purification to enrich full capsids ...
Kevin Vera, Ivan Gajic, Praveen Kusumanchi, Angela Andaluz, Gabrielle Dela Pena, Clifford A. Froelich, Elizabeth Higgins, Jennifer Johnston, Seyed Pouria Motevalian   +8 more
wiley   +1 more source

Qualidade do ar interno de uma instituição de ensino superior

Bioscience Journal, 2010
Avaliar a qualidade microbiológica do ar interno de uma instituição de ensino superior de Itumbiara-GO. Foram avaliadas 51 salas de aula, incluindo os laboratórios de química, zoologia e microbiologia e o ar do pátio externo da Instituição para uma ...
Gilsimeire Rodrigues Morais, Marcos Almeida Da Silva, Marcelo Victor de Carvalho, Jaqueline Gomes Souza Santos, Elias José Oliveira von Dolinger, Denise von Dolinger Brito   +5 more
doaj  

Rapid inactivation of aerosolised influenza virus using low-concentration gaseous hypochlorous acid

Scientific Reports
Effective infection control measures are crucial for limiting pathogen transmission, including aerosol infections. Several instances of the use of hypochlorous acid solution spray to inactivate airborne viruses have been reported.
Koki Narihata, Masaru Minamiguchi, Miki Hata, Mitsuhiko Ueda, Shinji Yoshida, Yoshihiro Sakoda   +5 more
doaj   +1 more source

Regenerative perfusion bioreactor for biologics production with lower COGs

Biotechnology Progress, EarlyView.
Abstract Perfusion bioreactor systems enable intensified bioprocessing with high cell densities and volumetric productivities in monoclonal antibody (mAb) manufacturing. However, their widespread adoption remains constrained by the high consumption of chemically defined cell culture media.
Eric Wynne, Dohyun Park, Hourieh Ahi, Jaeweon Lee, Seongkyu Yoon, Jongyoon Han   +5 more
wiley   +1 more source

Ninth Flyer Fall_1998

, 2014
The quarterly newsletter, The Ninth Flyer, published by the Ninth Air Force Association, Inc.
9th Air Force Association
core  

Impact of single‐use bioreactor bag materials on Spodoptera frugiperda cell expansion for recombinant adeno‐associated virus manufacturing

Biotechnology Progress, EarlyView.
Abstract Recombinant adeno‐associated virus production for gene therapy applications commonly relies on the Spodoptera frugiperda 9 (Sf9) baculovirus infection platform. The process encompasses cell expansion from flasks through intermediate‐scale bioreactors to large‐scale production.
Min Tae Park, Seyed Pouria Motevalian
wiley   +1 more source

Economic and environmental implications of the development of UASB reactors in Mexico for sustainable industrial wastewater treatment

The Canadian Journal of Chemical Engineering, EarlyView.
Abstract The objective of this work is to demonstrate that the inclusion of an up‐flow anaerobic sludge bed (UASB reactor) within an industrial wastewater treatment plant reduces the plant's investment and operating costs compared to a system based solely on conventional complete‐mix activated sludge (CMAS), operating under the same design principles ...
Juan Manuel Morgan‐Sagastume, Adalberto Noyola   +1 more
wiley   +1 more source