Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Transboundary Air Pollution Transport of PM10 and Benzo[a]pyrene in the Czech–Polish Border Region
Atmosphere, 2022 The article is occupied with the evaluation of the transboundary transport of pollutants in the Czech–Polish border region (between the Moravian-Silesian region and the Silesian Voivodeship) in Central Europe.
Vladimíra Volná +3 more
doaj +1 more source
Air quality impact of a decision support system for reducing pollutant emissions: CARBOTRAF [PDF]
, 2014 Traffic congestion with frequent “stop & go” situations causes substantial pollutant emissions. Black carbon (BC) is a good indicator of combustion-related air pollution and results in negative health effects.
Assamer, J +18 more
core
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Aerosol and Air Quality ResearchDue to their small size and ability to penetrate deeply into the respiratory system, ultrafine particles (UFP) pose a significant health risk. Their concentrations and sources are not consistently monitored and regulated in urban areas, including Paris ...
Grégory Abbou +7 more
doaj +1 more source
Asian Journal of Atmospheric Environment, 2021 We conducted spatiotemporal assessments of ozone in South Korea from 1990–2020 to evaluate trends and compare changes in compliance based on South Korean, US, and EU standards.
Jeonghwan Kim +6 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Aerosol–computational fluid dynamics modeling of ultrafine and black carbon particle emission, dilution, and growth near roadways [PDF]
Atmospheric Chemistry and Physics, 2014 Many studies have shown that on-road vehicle emissions are the dominant source of ultrafine particles (UFPs; diameter < 100 nm) in urban areas and near-roadway environments.
L. Huang +9 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Performance of Aether Low-Cost Sensor Device for Air Pollution Measurements in Urban Environments. Accuracy Evaluation Applying the Air Quality Index (AQI) [PDF]
, 2021 Georgios Spyropoulos +2 more
openalex +1 more source