Results 51 to 60 of about 3,328,773 (296)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Temporal variations in health risk indices and combustion-derived components of PM1.0: Focus on terephthalate and levoglucosan

Heliyon
This study evaluated the health risks and chemical composition of PM1.0 and PM2.5 in Incheon, South Korea, emphasizing the critical role of particle size in public health impacts.
Myoungki Song, Seoyeong Choe, Sea-Ho Oh, Minyoung Sung, Ji Yun Jung, Jinsoo Choi, Joonyoung Ahn, Jungmin Park, Myungsoo Yoo, Jinsoo Park, Min-Suk Bae   +10 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Transboundary Air Pollution Transport of PM₁₀ and Benzo[a]pyrene in the Czech–Polish Border Region

Atmosphere, 2022
The article is occupied with the evaluation of the transboundary transport of pollutants in the Czech–Polish border region (between the Moravian-Silesian region and the Silesian Voivodeship) in Central Europe.
Vladimíra Volná, Daniel Hladký, Radim Seibert, Blanka Krejčí   +3 more
doaj   +1 more source

Crossroads for Federal Enforcement of the Clean Air Act [PDF]

, 1996
A major goal of the Clean Air Act 1 (hereinafter CAA or Act ) is to protect and enhance the quality of the Nation\u27s air resources. 2 The Act uses a two tiered approach to accomplish this goal.
Martin, Joyce M.
core   +1 more source

Heat waves and human well-being in Madrid (Spain) [PDF]

, 2019
Heat waves pose additional risks to urban spaces because of the additional heat provided by urban heat islands (UHIs) as well as poorer air quality.
Allende, Fernando, Fernández, Felipe, Martilli, Alberto, Rasilla, Domingo   +3 more
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ultrafine Particles Monitoring in Paris: From Total Number Concentrations to Size Distributions Measurements

Aerosol and Air Quality Research
Due to their small size and ability to penetrate deeply into the respiratory system, ultrafine particles (UFP) pose a significant health risk. Their concentrations and sources are not consistently monitored and regulated in urban areas, including Paris ...
Grégory Abbou, Véronique Ghersi, François Gaie-Levrel, Anne Kauffmann, Mikael Reynaud, Christophe Debert, Philippe Quénel, Alexia Baudic   +7 more
doaj   +1 more source

Long-term Assessment of Ozone Nonattainment Changes in South Korea Compared to US, and EU Ozone Guidelines

Asian Journal of Atmospheric Environment, 2021
We conducted spatiotemporal assessments of ozone in South Korea from 1990–2020 to evaluate trends and compare changes in compliance based on South Korean, US, and EU standards.
Jeonghwan Kim, Jimin Lee, Jin-Seok Han, Jinsoo Choi, Dai-Gon Kim, Jinsoo Park, Gangwoong Lee   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source