Results 41 to 50 of about 5,612,666 (297)

Flying wing flow separation control by microsecond pulsed dielectric barrier discharge at high Reynolds number

AIP Advances, 2019
In this study, a microsecond pulsed dielectric barrier discharge (μs-DBD) plasma actuator is utilized to improve the aerodynamic performance of a flying wing.
Zhong-guo Niu, Jie Liu, Hua Liang, Li-ke Xie, Zhi Su   +4 more
doaj   +1 more source

Is the High-Speed Rail Opening Environmentally Friendly? Taking the Difference-in-Differences Test in Jiangsu, China

Complexity, 2020
In view of rapid development of high-speed rail, the relationship between high-speed rail and air pollution needs to be tested and determined. Most research studies focused on the impact of high-speed rail on environmental pollution and just viewed high ...
Shijin Wang, Huiying Zhou, Guihong Hua
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Testing Method for Non-Isothermal Radial Wall Jets from Ceiling Diffusers Used in Building Ventilation

Energies
Diffusers producing radial jets attached to the ceiling are most often used in ventilation and air conditioning systems. In building ventilation, the temperature of the jet supplying the air into the rooms is usually different to the surrounding air ...
Maria Hurnik
doaj   +1 more source

Safety, speed, and effectiveness of air transportation for neonates

Pediatrics International, 2021
AbstractBackground : In Japan, 44.3% of neonates are delivered in private clinics without an attending pediatrician. Obstetricians in the clinics must resuscitate asphyxiated neonates in unstable condition, such as respiratory failure, and they are frequently transferred to tertiary perinatal medical centers.
Eiji Hirakawa, Satoshi Ibara, Hideaki Yoshihara, Masato Kamitomo, Yuichi Kodaira, Masaya Kibe, Chie Ishihara, Yoshiki Naito, Masakatsu Yamamoto, Tsuyoshi Yamamoto, Tatsu Takayama, Tomonori Kurimoto, Yuta Mikami, Hiroshi Ohashi   +13 more
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

A Simulation and Experiment on the Optimization Design of an Air Outlet Structure for an Air-Assisted Sprayer

Agriculture, 2023
In response to the issues of low-velocity zones and non-uniform jet velocity distribution in the airflow field of traditional air-assisted orchard sprayers, an arc-shaped air outlet suitable for axial-flow air-assisted systems is designed.
Shuaijie Jing, Longlong Ren, Yue Zhang, Xiang Han, Ang Gao, Baoyou Liu, Yuepeng Song   +6 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source