Results 61 to 70 of about 11,278,576 (325)
Modelling daily water temperature from air temperature for the Missouri River
The bio-chemical and physical characteristics of a river are directly affected by water temperature, which thereby affects the overall health of aquatic ecosystems. It is a complex problem to accurately estimate water temperature.
Senlin Zhu, E. Nyarko, M. Hadzima-Nyarko
semanticscholar +1 more source
An analytical investigation of the physical dimensions of natural convection flow on a vertical heated plate [PDF]
Analytical results of the boundary layer of natural convection air flow on a vertical heated plate are presented for both isothermal and constant heat flux plates.
Alzwayi, A.S., Paul, M.C.
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Risk Assessment of Freezing–Thawing Hazards in the Daxing’anling Forest Region
The Daxing’anling forest region represents a crucial forestry hub in China and confronts some of the nation’s most severe freezing–thawing hazards. This study delved into the temporal trends and spatial distributions of various parameters related to ...
Kezheng Chen, Shuai Huang
doaj +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Stability of clay particle-coated microbubbles in alkanes against dissolution induced by heating [PDF]
We investigated the dissolution and morphological dynamics of air bubbles in alkanes stabilized by fluorinated colloidal clay particles when subjected to temperature changes.
Achakulwisut, Kanvara +5 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The paper presents long-term changes in water temperature in two rivers, Oder and Neman, with catchments showing different climatic conditions (with dominance of marine climate in the case of the Oder and continental climate in the case of the Neman ...
Adam Choiński +7 more
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source

