Results 61 to 70 of about 3,003,880 (282)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Method and apparatus for checking fire detectors [PDF]
A fire detector checking method and device are disclosed for nondestructively verifying the operation of installed fire detectors of the type which operate on the principle of detecting the rate of temperature rise of the ambient air to sound an alarm ...
Clawson, G. T.
core +1 more source
Pollutant dispersion in a developing valley cold-air pool [PDF]
Pollutants are trapped and accumulate within cold-air pools, thereby affecting air quality. A numerical model is used to quantify the role of cold-air-pooling processes in the dispersion of air pollution in a developing cold-air pool within an alpine ...
A Gohm +46 more
core +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Experimental Design and Research of Air Spring Low Temperature Properties
Low temperature test on the air spring is an important means for improving alpine EMUs bogie dynamic performance. Low temperature working condition of air spring was analyzed briefly, and air spring full two-dimensional load testing scheme at low ...
Liqun PENG +3 more
doaj
Apparatus for supplying conditioned air at a substantially constant temperature and humidity [PDF]
The apparatus includes a supply duct coupled to a source of supply air for carrying the supply air therethrough. A return duct is coupled to the supply duct for carrying return conditioned air therethrough. A temperature reducing device is coupled to the
Obler, H. D.
core +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Comparison of air temperature measured in a vineyard canopy and at a standard weather station.
The complex environment within a crop canopy leads to a high variability of the air temperature within the canopy, and, therefore, air temperature measured at a weather station (WS) does not represent the internal energy within a crop.
Andrés Javier Peña Quiñones +4 more
doaj +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Dynamics and Modern Temperature Regime of Calendar Summer over Stavropol Height
Introduction. The article is devoted to calculation and analysis dynamics and modern temperature regime of calendar summer of over Stavropol height, which is one the main ground features of the Central Pre-Caucasus.
V. I. Volkova +3 more
doaj

