Results 31 to 40 of about 3,507,302 (280)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Reconnaissance Mission Conducted by UAV Swarms Based on Distributed PSO Path Planning Algorithms

open access: yesIEEE Access, 2019
Reconnaissance mission has a wide application in both civil and military fields, which provides intelligence and basis for the following decision-making to accomplish certain goals.
Yubing Wang   +5 more
doaj   +1 more source

Air Pollution Measurements in Traffic Tunnels [PDF]

open access: yesEnvironmental Health Perspectives, 1994
Air pollution measurements during April 1991 are reported from the Craeybeckx highway tunnel in Antwerp, Belgium. The tunnel was used daily by an average of 45,000 vehicles, of which 60% were gasoline fueled passenger cars, 20% diesel cars, and 20% trucks. Of the gasoline cars, only 3% had three-way catalysts.
R, De Fré   +2 more
openaire   +2 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Volcanic Ash Region Path Planning Based on Improved A-Star Algorithm

open access: yesJournal of Advanced Transportation, 2022
In civil aviation flight path planning, in order to effectively reduce the safety threat caused by the volcanic ash area to the civil aviation flight, factors such as the speed and acceleration of the aircraft in the volcanic ash area must be considered.
Lan Ma   +3 more
doaj   +1 more source

Air traffic complexity in future Air Traffic Management systems

open access: yesJournal of Aerospace Operations, 2012
In this paper we study the issue of characterizing the complexity of air traffic to support Air Traffic Management (ATM) operations. We discuss, in particular, the features of a complexity metric that are relevant for application to future ATM systems where part of the responsibility for separation assurance and trajectory management operations is ...
PRANDINI, MARIA, V. Putta, J. Hu
openaire   +2 more sources

Air‐Pressure–Actuated Vibroacoustic Metamaterial With Tunable Bandgap: Design, Modeling, and Characterization

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the design, modeling, and characterization of air‐pressure–actuated programmable vibroacoustic metamaterials (PVAMM). The study focuses on leveraging air pressure to dynamically tune resonance frequencies for effective noise attenuation.
William Kaal   +2 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Research on Aircraft Turbulence Early Warning Technology Driven by Ensemble Kalman Filter and Multiscale Information

open access: yesJournal of Advanced Transportation
Flight turbulence poses a severe threat to aviation safety, and achieving its effective early warning is a critical challenge to be addressed. To overcome the limitations of traditional methods reliant on single information sources or advanced remote ...
Hongyong Wang   +3 more
doaj   +1 more source

Optimal Sensor Deployment and Velocity Configuration With Hybrid TDOA and FDOA Measurements

open access: yesIEEE Access, 2019
Source localization based on the hybrid time-difference-of-arrival (TDOA) and frequency-difference-of-arrival (FDOA) measurements from distributed sensors is an essential problem in wireless sensor networks (WSNs).
Weijia Wang   +4 more
doaj   +1 more source

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