Results 101 to 110 of about 638,049 (357)

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

open access: yesAdvanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu   +20 more
wiley   +1 more source

Research on the Method of Unbalanced Target Allocation in Multi-aircraft Air Combat Command and Guidance

open access: yesHangkong gongcheng jinzhan, 2018
There are just a few unbalanced target assignment models in multi-aircraft air combat command and guidance, so a new unbalanced target assignment method for multi-aircraft air combat is proposed.
Gao Yangyang, Yu Minjian, Yang Jie
doaj   +1 more source

Navigation/traffic control satellite mission study. Volume 3 - System concepts [PDF]

open access: yes
Satellite network for air traffic control, solar flare warning, and collision ...
Caprioglio, A. F.   +4 more
core   +1 more source

Aircraft Conflict Resolution by Genetic Algorithm and B-Spline Approximation [PDF]

open access: yes, 2010
International audienceConflict resolution has always been a sensitive matter in air-traffic management. Current European projects aim partial or total automation of air-traffic control to deal with the constant growth of air-traffic.
Delahaye, Daniel   +3 more
core   +1 more source

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

open access: yesAdvanced Science, EarlyView.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan   +14 more
wiley   +1 more source

A SVM Approach of Aircraft Conflict Detection in Free Flight

open access: yesJournal of Advanced Transportation, 2018
Probabilistic conflict detection methods typically require high computational burden to deal with complex multiaircraft conflict detection. In this article, aircraft conflict detection is considered as a binary classification problem; therefore, it can ...
Xu-rui Jiang   +4 more
doaj   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang   +15 more
wiley   +1 more source

Bi-weekly Report, July 8, 1949 [PDF]

open access: yes, 1949
Bi-weekly progress report of the Air Traffic Control Project ...
Air Traffic Control Project Staff
core  

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