Results 51 to 60 of about 12,457,896 (279)

Multi-constraint calibrated GP2SFCA identifies dual vulnerability in private-vehicle access to Tertiary Grade‑A emergency care of Chengdu

Scientific Reports
Evaluating private vehicle access to emergency care is crucial for public health resource planning. However, conventional models frequently depend on static traffic data and subjective parameters, neglecting the behavioral complexities involved in ...
Chen Luo, Chunyang Liu, Tianshun Ma, Xinrong Hu, Haoyuan Li, Xutong Wang   +5 more
doaj   +1 more source

A Biomimetic PLK1 Nanodelivery System Promotes Migrasome‐Mediated Mitocytosis to Restore Efferocytosis and Functional Recovery After Spinal Cord Injury

Advanced Science, EarlyView.
MM‐NPs@PLK1 are formed by encapsulating PLK1 plasmids within CBP5 and coating the nanocomplexes with macrophage membranes. After macrophage‐associated uptake, the NPs@PLK1 enter the cytoplasm and release the PLK1‐encoding plasmid in response to elevated intracellular ROS levels.
Zhenxin Hu, Haoli Wang, Jing Huang, Junhua Zhou, Jialong Hou, Hanwei Miao, Huixin Tan, Yining Wang, Hao Hu, Na Li, Pengcheng Qiu, Hongyu Zhang, Da He, Qingqing Wang   +13 more
wiley   +1 more source

Air traffic complexity in future Air Traffic Management systems

Journal of Aerospace Operations, 2012
In this paper we study the issue of characterizing the complexity of air traffic to support Air Traffic Management (ATM) operations. We discuss, in particular, the features of a complexity metric that are relevant for application to future ATM systems where part of the responsibility for separation assurance and trajectory management operations is ...
PRANDINI, MARIA, V. Putta, J. Hu
openaire   +2 more sources

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

A Review of Machine Learning Methods for Aviation Turbulence Identification and Forecasting

IEEE Access
Aviation turbulence remains a major challenge to aviation safety, frequently causing passenger injuries. However, traditional turbulence detection and forecasting methods based on airborne equipment and operational numerical weather prediction (NWP) lack
Kenan Li, Bosi Huang, Hongyong Wang, Ning Fu, Haiwen Liu, Xin Yan, Yongzhe Pan   +6 more
doaj   +1 more source

The European Air Traffic Flow Management Problem

Transportation Science, 2006
Air traffic flow management in Europe has to deal as much with capacity constraints in en route airspace as with the more usual capacity constraints at airports. The en route sector capacity constraints, in turn, generate complex interactions among traffic flows. We present a deterministic optimization model for the European air traffic flow management
LULLI, GUGLIELMO, Odoni, A.
openaire   +2 more sources

Nanocatalytic Immunotherapy Targeting Tumor‐Resident Intracellular Bacteria for Triple‐Negative Breast Cancer Treatment and Metastasis Suppression

Advanced Science, EarlyView.
Bacteria residing within tumor cells contribute to breast cancer progression, but few therapies target their elimination. FeSe2 nanosheets coated with cancer cell membranes accumulate in tumors and generate reactive oxygen species under ultrasound, killing tumor cells and their harbored bacteria at the same time.
Xiaojing Leng, Tao Jiang, Zhao Guo, Zhimin Zhang, Yihan Chen, Pan Li, Min Ge, Han Lin, Liang Zhang   +8 more
wiley   +1 more source

Research on Civil Aviation Airport Site Selection Considering Group Consensus Level Under Large-Scale Uncertain Information

International Journal of Computational Intelligence Systems
In response to the decision-making challenges posed by large-scale information and complex data sources in civil aviation airport site selection, this paper proposes a novel method that integrates group consensus within a framework of substantial ...
Rui Wang, Jing-Han Zeng, Jing-Yang Huang, Rui Kang, Jiang Yuan, Qing-Wei Zhong   +5 more
doaj   +1 more source

Study on Longitudinal Collision Risk of Closely Spaced Parallel Runways Paired Approach

Promet (Zagreb)
This study asserts that paired aircraft can withstand specific wake turbulence levels and explores the longitudinal collision risk in closely spaced parallel runway approaches. The goal is to enhance the safety margin of the paired approach and allow for
Fei LU, Jian ZHANG, Erli ZHAO, Jingjie TENG   +3 more
doaj   +1 more source

Conformal Reconfigurable Intelligent Surfaces: A Cylindrical Geometry Perspective

Advanced Electronic Materials, EarlyView.
Cylindrical reconfigurable intelligent surfaces are explored for low‐complexity beam steering using one‐bit meta‐atoms. A multi‐level modeling approach, including optimization‐based synthesis, demonstrates that even minimal hardware can support directive scattering.
Filippo Pepe, Ivan Iudice, Giuseppe Castaldi, Marco Di Renzo, Vincenzo Galdi   +4 more
wiley   +1 more source