Results 31 to 40 of about 144,156 (294)

Marketing strategy for green transport and logistics infrastructure innovative projects’ development [PDF]

E3S Web of Conferences
The global push to sustainable development has significantly reshaped the transport and logistics sectors. This article explores the critical role of marketing strategy in accelerating the development and adoption of green transport and logistics ...
Vasylenko Igor, Voitsehovskiy Viktor, Beketov Yurii, Viniukov-Proshchenko Artur, Gabrielova Tetiana, Lytvynenko Larysa   +5 more
doaj   +1 more source

A Proposal and Analysis of New Realistic Sets of Benchmark Instances for Vehicle Routing Problems with Asymmetric Costs

Applied Sciences, 2021
Despite their importance, relatively little attention has been paid to vehicle routing problems with asymmetric costs (ACVRPs), or their benchmark instances.
Keyju Lee, Junjae Chae
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Finite-Time Resource Allocation Algorithm for Networked Fractional Nonlinear Agents

Fractal and Fractional
This paper investigates finite-time resource allocation problems (RAPs) for uncertain nonlinear fractional-order multi-agent systems (FOMASs), considering global equality and local inequality constraints.
Qingxiang Ao, Cheng Li, Jiaxin Yuan, Xiaole Yang   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Study on Green Airport Construction and Aviation Pollution Control: A Case Study of Four International Airports

Atmosphere
In the era of globalization and information technology, the aviation industry has experienced rapid growth. However, the increase in flight numbers has exacerbated environmental issues such as exhaust emissions and noise pollution, raising significant ...
Shiguo Deng, Shuolei Zhou, Li Zhang, Jiani Zhao   +3 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Industry Snapshots: Uses of Transportation: 2015 [PDF]

The Bureau of Transportation Statistics (BTS) estimates that transportation directly created $692.0 billion of economic activity by moving goods in 2014.
Firestine, Theresa, United States. Department of Transportation. Bureau of Transportation Statistics   +1 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source