Results 41 to 50 of about 101,193 (261)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

TSGformer: A Unified Temporal–Spatial Graph Transformer with Adaptive Cross-Scale Modeling for Multivariate Time Series

open access: yesSystems
Multivariate time series forecasting requires modeling complex and evolving spatio-temporal dependencies as well as frequency-domain patterns; however, the existing Transformer-based approaches often struggle to effectively capture dynamic inter-series ...
Yan Chen, Cheng Li, Xiaoli Zhao
doaj   +1 more source

Transport-logistic clusters’ passenger and cargo flows long term predictive modelling [PDF]

open access: yesE3S Web of Conferences
The relevance of the research is determined by the need for a long-term vision of the development of transport-logistics clusters and the needs that arise from the need to model flows.
Vasylenko Igor   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Distributed Adaptive Optimization Algorithm for High-Order Nonlinear Multi-Agent Stochastic Systems with Lévy Noise

open access: yesEntropy
An adaptive neural network output-feedback control strategy is proposed in this paper for the distributed optimization problem (DOP) of high-order nonlinear stochastic multi-agent systems (MASs) driven by Lévy noise.
Hui Yang, Qing Sun, Jiaxin Yuan
doaj   +1 more source

Justification of the acceptability of a hybrid approach to passenger and freight flows' predictive modelling in the context of sustainable development [PDF]

open access: yesE3S Web of Conferences
The relevance of the study is determined by the need for more accurate long-term forecasting in modeling passenger and freight flows. The methodological basis of the study consists of methods of analysis and forecasting of time series, methods of ...
Shapoval Ganna   +5 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Study on the Complexity Evolution of the Aviation Network in China

open access: yesSystems
As China’s economy grows and travel demand increases, its aviation market has evolved to become the second-largest in the world. This study presents a pioneering analysis of China’s aviation network evolution (1990–2024) by integrating temporal dynamics ...
Shuolei Zhou, Cheng Li, Shiguo Deng
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy