Results 101 to 110 of about 783,276 (359)

Lung‐Penetrating Biomimetic Extracellular Vesicle Spherical Nucleic Acids for Pulmonary Fibrosis Therapy Through ROS Scavenging and Anti‐Inflammatory Effects

open access: yesAggregate, EarlyView.
This work describes a biomimetic extracellular vesicle‐spherical nucleic acid (BEV‐SNA) platform for idiopathic pulmonary fibrosis (IPF) therapy. BEV‐SNA is composed of mechanically extruded BEVs from primary MSCs and cholesterol‐modified ssDNA that are assembled through hydrophobic interactions.
Saiyun Lou   +11 more
wiley   +1 more source

Analysis of the Navigation of Magnetic Microrobots through Cerebral Bifurcations for Targeted Drug Delivery

open access: yesAdvanced Intelligent Systems, EarlyView.
The motion of magnetic microrobots through cerebral bifurcations depends on various parameters such as the microrobots size, the blood velocity, and the imposed magnetic field gradients, among others. This work presents an in‐depth analysis of the effects of these parameters and equations predicting the required magnetic gradients based on the ...
Pedro G. Alves   +10 more
wiley   +1 more source

Mesenchymal stromal cells reduce inflammation and improve lung function in a mouse model of cystic fibrosis lung disease

open access: yesScientific Reports
Mesenchymal stromal cells (MSCs) are multipotent adult stem cells which possess immunomodulatory and repair capabilities. In this study, we investigated whether MSC therapy could modulate inflammation and lung damage in the lungs of Scnn1b-transgenic ...
Declan F. Doherty   +9 more
doaj   +1 more source

CIRCULATORY EFFECTS OF RAISED AIRWAY PRESSURE DURING CYCLOPROPANE ANESTHESIA IN MAN 1 [PDF]

open access: bronze, 1951
Henry L. Price   +4 more
openalex   +1 more source

Mast-cell infiltration of airway smooth muscle in asthma.

open access: yesNew England Journal of Medicine, 2002
BACKGROUND Asthma and eosinophilic bronchitis are characterized by similar inflammatory infiltrates in the submucosa of the lower airway. However, eosinophilic bronchitis differs from asthma in that there is no variable airflow obstruction or airway ...
C. Brightling   +5 more
semanticscholar   +1 more source

A Magnetically Transformable Twisting Millirobot for Cargo Delivery at Low Reynolds Number

open access: yesAdvanced Intelligent Systems, EarlyView.
Herein, a soft millirobot, TwistBot, that transforms from a flat shape to a helical shape to propel in fluids at low Reynolds number is reported. Its geometry is optimized by numerical simulation and validated by experiments to effectively propel and deliver solid cargos.
Moonkwang Jeong   +3 more
wiley   +1 more source

PM2.5 Induced Nasal Mucosal Barrier Dysfunction and Epithelial–Mesenchymal Transition to Promote Chronic Rhinosinusitis Through IL4I1-AhR Signaling Pathway

open access: yesToxics
Environmental pollutants like PM2.5 contribute to chronic rhinosinusitis (CRS). The aryl hydrocarbon receptor (AhR), a contaminant sensor linked to tryptophan metabolites, is regulated by IL4I.
Yue Wang   +7 more
doaj   +1 more source

Post Intubation Phonatory Insufficiency: A novel surgical treatment

open access: yesOtolaryngology Case Reports, 2021
Post Intubation Phonatory Insufficiency as a result of prolonged intubation in premature neonates is a challenging condition to diagnose and treat.An endotracheal tube can cause an erosive injury to the medial surface of the arytenoid cartilage resulting
Bronagh Lang   +3 more
doaj  

Design, Modeling, and Control of a Soft Robotic Diaphragm‐Assist Device in a Respiratory Simulator

open access: yesAdvanced Intelligent Systems, EarlyView.
A soft robotic diaphragm‐assist device using fabric‐based pneumatic actuators with a 2‐step control system to optimize synchronization and support is introduced. This system can detect the initiation of breathing to trigger assistance and regulate pressures to provide the correct level of inhalation augmentation. Validation and testing are completed on
Diego Quevedo‐Moreno   +5 more
wiley   +1 more source

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