A Microfluidic Model of Biomimetically Breathing Pulmonary Acinar Airways [PDF]
, 2016 Rami Fishler, Josué Sznitman
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Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]
, 2009 The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon +14 more
core
Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E
Advanced Science, EarlyView.Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple models, secondary necrosis occurred regardless of gasdermin E presence, challenging prior claims and redefining the understanding of how apoptotic cells ...
Shubhangi Gavali +9 more
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Endotracheal Metastasis Causing Airway Obstruction [PDF]
, 2020 Endotracheal metastasis, a critical complication of primary lung cancer, is an extremely rare lesion. A 73-year-old woman who had previously received treatment for lung cancer presented to our emergency department with dyspnea.
Fujiwara, Takashi +2 more
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Advanced Science, EarlyView.The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang +14 more
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Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Respiratory ResearchBackground Interleukin (IL)-26 is produced by T helper type 17 (Type 17) cells and exerts immunomodulatory plus antimicrobial effects. Previous studies show that local IL-26 concentrations in the airways are higher in patients with uncontrolled than in ...
Melissa A. Kovach +5 more
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In Vitro Study of the Suitability of Nanoparticles as a Vehicle for Gene Delivery into Airway Epithelium Cells [PDF]
, 2005 Martin Brzoska
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Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease [PDF]
, 2022 Yuan Zhan +10 more
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Evaluation of human obstructive sleep apnea using computational fluid dynamics. [PDF]
, 2019 Obstructive sleep apnea (OSA) severity might be correlated to the flow characteristics of the upper airways. We aimed to investigate the severity of OSA based on 3D models constructed from CT scans coupled with computational fluid dynamics (CFD ...
Jafari, Behrouz +4 more
core
Advanced Science, EarlyView.Heterogeneous distributions of elasticity parameters are learned from noisy displacement data using the Inverse Elasticity Physics‐Informed Neural Network (IE‐PINN). This approach integrates both data‐driven and physics‐driven methods to address the significant limitations faced by existing techniques.
Tatthapong Srikitrungruang +4 more
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