Results 121 to 130 of about 806,749 (357)
Systemic IL-26 correlates with improved asthma control in children sensitized to dog allergen
Background Interleukin (IL)-26 is produced by T helper type 17 (Type 17) cells and exerts immunomodulatory plus antimicrobial effects. Previous studies show that local IL-26 concentrations in the airways are higher in patients with uncontrolled than in ...
Melissa A. Kovach+5 more
doaj +1 more source
Single‐cell RNA sequencing reveals distinct immune responses to FLASH versus conventional dose rate irradiation in early radiation‐induced lung injury. FLASH irradiation reduces Ccrl2⁺ neutrophil infiltration, activates CD4⁺ CD40L⁺ Th cells, restrains pro‐inflammatory Mefv⁺ monocytes, and enhances epithelial repair via TGF‐β signaling, underscoring its
Hao Lu+10 more
wiley +1 more source
Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. [PDF]
The innate immune response of airway epithelial cells to airborne allergens initiates the development of T cell responses that are central to allergic inflammation.
Angkasekwinai, Pornpimon+14 more
core
Trial of Bronchodilator Drugs Given by Metered Aerosol with a Comparison of Two Bedside Methods of Estimating Airway Resistance [PDF]
B I Hoffbrand+3 more
openalex +1 more source
Airway spider or airway spiders? [PDF]
Flavia Petrini, Massimiliano Sorbello
openaire +3 more sources
PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan+17 more
wiley +1 more source
Cystic fibrosis of the pancreas: structural changes in peripheral airways [PDF]
John R. Esterly, Ella H. Oppenheimer
openalex +1 more source
Plant‐derived bioactive molecules with low solubility and permeability induce hepatocyte injury, though the mechanisms driving their hepatic effects remain poorly understood. This study identifies a novel transport pathway in which poorly soluble indirubin accumulates in the liver via macrophage‐mediated uptake in Peyer's patches, exacerbating hepatic ...
Yiqi Xu+9 more
wiley +1 more source
Multiple Bronchiolar Stenoses in a Patient with Generalized Airways Obstruction [PDF]
John R. Esterly, B. E. Heard
openalex +1 more source